Lexiscan Side Effects

Generic name: regadenoson

Note: This document contains side effect information about regadenoson. Some of the dosage forms listed on this page may not apply to the brand name Lexiscan.

Some side effects of Lexiscan may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to regadenoson: intravenous solution

Get emergency medical help if you have any of these signs of an allergic reaction while taking regadenoson (the active ingredient contained in Lexiscan) hives; difficulty breathing; swelling of your face, lips, tongue, or throat.

Tell your caregivers at once if you have a serious side effect such as:

• chest pain or heavy feeling, pain spreading to the arm or shoulder, nausea, sweating, general ill feeling;

• slow heart rate, weak pulse, fainting, slow breathing (breathing may stop);

• dangerously high blood pressure (severe headache, blurred vision, buzzing in your ears, anxiety, confusion, shortness of breath, uneven heart rate);

• seizure (convulsions);

• wheezing, trouble breathing; or

• feeling like you might pass out.

Less serious side effects of regadenoson may include:

• headache;

• dizziness;

• nausea, stomach discomfort, decreased sense of taste;

• mild chest discomfort; or

• warmth, redness, or tingly feeling under your skin.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to regadenoson: intravenous solution

Respiratory

Respiratory side effects including dyspnea (28%) have been reported.

Nervous system

Nervous system side effects including headache (26%) and dizziness (8%) have been reported.

Cardiovascular

Cardiovascular side effects have included tachycardia (22%), flushing (16%), premature ventricular contractions (14%), chest discomfort (13%), angina or ST segment depression (12%), Chest pain (7%), premature atrial contractions (7%), systolic blood pressure decreased greater than 35 mm Hg (7%), ventricular conduction abnormalities (6%) diastolic blood pressure decreased more than 25 mm Hg (4%), first-degree AV block (PR prolongation greater than 220 msec; 3%), second-degree AV block (less than 1%), AV conduction abnormalities (other than AV blocks; less than 1%).

Gastrointestinal

Gastrointestinal side effects including nausea (6%), abdominal discomfort (5%), and dysgeusia (5%) have been reported.

General

General side effects including feeling hot (5%) have been reported.

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