K-Phos No. 2 Side Effects

Generic Name: potassium phosphate / sodium phosphate

Note: This page contains information about the side effects of potassium phosphate / sodium phosphate. Some of the dosage forms included on this document may not apply to the brand name K-Phos No. 2.

Not all side effects for K-Phos No. 2 may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to potassium phosphate / sodium phosphate: oral tablet

In addition to its needed effects, some unwanted effects may be caused by potassium phosphate / sodium phosphate. In the event that any of these side effects do occur, they may require medical attention.

You should check with your doctor immediately if any of these side effects occur when taking potassium phosphate / sodium phosphate:

Incidence not known
  • Bone pain
  • convulsions
  • decreased urine output
  • dizziness
  • fast or irregular heartbeat
  • headache
  • joint pain
  • mental confusion
  • muscle cramps
  • numbness or tingling around the lips
  • numbness, tingling, pain, or weakness of the hands or feet
  • shortness of breath
  • swelling of the feet or lower legs
  • troubled breathing
  • unusual thirst
  • unusual tiredness or weakness
  • unusual weight gain
  • weakness or heaviness of the legs

Some of the side effects that can occur with potassium phosphate / sodium phosphate may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Incidence not known
  • Diarrhea
  • nausea
  • stomach pain
  • vomiting

For Healthcare Professionals

Applies to potassium phosphate / sodium phosphate: oral powder for reconstitution, oral tablet


There have been reports of a laxative effect occurring over the first few days of therapy. Lowering the dose usually reverses this effect; however, discontinuation of therapy is sometimes necessary.

Gastrointestinal side effects have included a laxative effect.

Gastrointestinal side effects associated with phosphate have included diarrhea, nausea, stomach pain, and vomiting.


Musculoskeletal side effects associated with phosphate have included bone and joint pain, and osteomalacia.

Musculoskeletal side effects associated with potassium and/or sodium have included muscle cramps.

Nervous system

Nervous system side effects associated with potassium and/or sodium have included headache, dizziness, mental confusion, seizures, weakness or heaviness of legs, unusual tiredness or weakness, numbness, tingling, pain, weakness of hands or feet, and numbness or tingling around lips.


Cardiovascular side effects associated with potassium and/or sodium have included fast or irregular heartbeat, shortness of breath, troubled breathing, and swelling of feet or lower legs.


Other side effects associated with potassium and/or sodium have included unusual weight gain and unusual thirst.


Renal side effects associated with potassium and/or sodium have included low urine output.

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