Infanrix (DTaP) Side Effects

Generic Name: diphtheria and tetanus toxoids / pertussis, acellular

Note: This page contains information about the side effects of diphtheria and tetanus toxoids / pertussis, acellular. Some of the dosage forms included on this document may not apply to the brand name Infanrix (DTaP).

Not all side effects for Infanrix (DTaP) may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to diphtheria and tetanus toxoids / pertussis, acellular: intramuscular suspension

In addition to its needed effects, some unwanted effects may be caused by diphtheria and tetanus toxoids / pertussis, acellular. In the event that any of these side effects do occur, they may require medical attention.

If any of the following side effects occur while taking diphtheria and tetanus toxoids / pertussis, acellular, check with your doctor or nurse immediately:

Less common
  • Collapse or shock-like state
  • crying for 3 hours or more
  • fever over 102.2 °F
  • redness or swelling of 4 inches or more at the injection site
  • seizures (convulsions)
  • severe pain at the injection site
Incidence not known
  • Agitation
  • back pain
  • black, tarry stools
  • bleeding gums
  • bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
  • blood in the urine or stools
  • bloody nose
  • bluish color of the fingernails, lips, skin, palms, or nail beds
  • blurred vision
  • confusion
  • cough
  • diarrhea
  • difficulty with swallowing
  • dizziness
  • drowsiness
  • fast heartbeat
  • hallucinations
  • headache
  • hoarseness
  • irritability
  • irritation
  • joint pain, stiffness, or swelling
  • loss of bladder control
  • loss of consciousness
  • loss of strength or energy
  • muscle pain or weakness
  • nausea and vomiting
  • pain or cramping in the abdomen or stomach
  • pinpoint red spots on the skin
  • puffiness or swelling of the eyelids or around the eyes, face, lips, or tongue
  • rash with flat lesions or small raised lesions on the skin
  • screaming
  • shortness of breath
  • sleepiness or unusual drowsiness
  • sneezing
  • sore throat
  • stiff neck
  • swollen, painful, or tender lymph glands in the neck, armpit, or groin
  • tightness in the chest
  • total body jerking
  • unusual bleeding or bruising
  • unusual tiredness or weakness (sudden and severe)

Some of the side effects that can occur with diphtheria and tetanus toxoids / pertussis, acellular may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common
  • Fever of 99.5 °F or more
  • fussiness
  • loss of appetite
  • mild pain, redness, swelling, or tenderness at the injection site
  • restlessness
  • weight loss
Incidence not known
  • Crying
  • ear pain

For Healthcare Professionals

Applies to diphtheria and tetanus toxoids / pertussis, acellular: intramuscular suspension

Local

Local side effects have included erythema, swelling, tenderness, and pain.[Ref]

Hypersensitivity

Hypersensitivity side effects have included rare reports of anaphylactic reactions (ie, hives, swelling of the mouth, difficulty breathing, hypotension, or shock). Arthus-type hypersensitivity reactions, characterized by severe local reactions (generally starting 2 to 8 hours after an injection), may follow receipt of tetanus toxoid.[Ref]

General

General side effects have included fever greater than 101 degrees F (rectal), high-pitched cry, persistent cry, and irritability.[Ref]

Gastrointestinal

Gastrointestinal side effects have included anorexia and vomiting.[Ref]

Nervous system

Nervous system side effects have included drowsiness. A review by the Institute of Medicine (IOM) found evidence for a causal relationship between tetanus toxoid and both brachial neuritis and Guillain-Barre syndrome.[Ref]

References

1. "Product Information. Tripedia (diphtheria/pertussis, acellular/tetanus)." Aventis Pharmaceuticals, Swiftwater, PA.

2. "Product Information. Daptacel (diphtheria/pertussis, acellular/tetanus)." Aventis Pasteur Inc, Swiftwater, PA.

More about Infanrix (DTaP) (diphtheria and tetanus toxoids / pertussis, acellular)

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