In-111 Zevalin Side Effects

Generic name: ibritumomab

Note: This document contains side effect information about ibritumomab. Some of the dosage forms listed on this page may not apply to the brand name In-111 Zevalin.

Some side effects of In-111 Zevalin may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

Applies to ibritumomab: intravenous kit

Some people receiving an ibritumomab (the active ingredient contained in In-111 Zevalin) injection have had a reaction to the infusion (when the medicine is injected into the vein). Tell your caregiver right away if you feel dizzy, nauseated, light-headed, sweaty, itchy, or have a fast heartbeat, trouble breathing, chest pain or heavy feeling, or pain spreading to the arm or shoulder. These reactions can occur during the injection or within 24 hours afterward.

Get emergency medical help if you have any of these signs of an allergic reaction while taking ibritumomab: hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have a serious side effect such as:

• pain, burning, redness, or skin changes where the medicine was injected;

• fever with chills, body aches, and other flu symptoms;

• easy bruising or bleeding, unusual weakness;

• white patches or sores inside your mouth or on your lips; or

• severe skin reaction -- fever, sore throat, swelling in your face or tongue, burning in your eyes, skin pain, followed by a red or purple skin rash that spreads (especially in the face or upper body) and causes blistering and peeling.

Less serious side effects of ibritumomab may include:

• nausea, vomiting, loss of appetite;

• anxiety;

• dizziness; or

• joint pain.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

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