Hydrocodone / phenylephrine Side Effects

Not all side effects for hydrocodone / phenylephrine may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to hydrocodone / phenylephrine: liquid, syrup

Check with your doctor if any of these most COMMON side effects persist or become bothersome:

Dizziness; drowsiness, excitability; headache; nausea; nervousness or anxiety; trouble sleeping; weakness.

Seek medical attention right away if any of these SEVERE side effects occur while taking hydrocodone / phenylephrine:

Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; severe drowsiness; tremor.

For Healthcare Professionals

Applies to hydrocodone / phenylephrine: oral liquid, oral syrup

Nervous system

Nervous system side effects have included drowsiness, nervousness, insomnia, and headache.

Gastrointestinal

Gastrointestinal side effects have included nausea and constipation.

Respiratory

Respiratory side effects have included respiratory depression.

Psychiatric

Psychiatric side effects have included addiction.

General

General side effects have included lassitude,and giddiness,

Genitourinary

Genitourinary side effects have included urinary retention in patients with prostatic hypertrophy.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate safety, effectiveness, or appropriateness for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of materials provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the substances you are taking, check with your doctor, nurse, or pharmacist.

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