FUDR Side Effects
Generic name: floxuridine
Note: This document contains side effect information about floxuridine. Some of the dosage forms listed on this page may not apply to the brand name FUDR.
Some side effects of FUDR may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to floxuridine: injection powder for solution
Along with its needed effects, floxuridine (the active ingredient contained in FUDR) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Also, because of the way these medicines act on the body, there is a chance that they might cause other unwanted effects that may not occur until months or years after the medicine is used. These delayed effects may include certain types of cancer, such as leukemia. Discuss these possible effects with your doctor.
Check with your doctor immediately if any of the following side effects occur while taking floxuridine:More common
- sores in mouth and on lips
- stomach pain or cramps
- Black, tarry stools
- nausea and vomiting
- scaling or redness of hands or feet
- swelling or soreness of the tongue
- Blood in urine or stools
- cough or hoarseness
- fever or chills
- lower back or side pain
- painful or difficult urination
- pinpoint red spots on skin
- trouble in walking
- unusual bleeding or bruising
- yellow eyes or skin
Some side effects of floxuridine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:Less common or rare
- Loss of appetite
- skin rash or itching
This medicine sometimes causes temporary thinning of hair. After treatment with floxuridine has ended, normal hair growth should return.
For Healthcare Professionals
Applies to floxuridine: injectable powder for injection
The manufacturer reports that adverse reactions to the arterial infusion of floxuridine (the active ingredient contained in FUDR) are generally related to the procedural complications of regional arterial infusion. The procedural complications of regional arterial infusion include arterial aneurysm, arterial ischemia, arterial thrombosis, embolism, fibromyositis, thrombophlebitis, hepatic necrosis, abscesses, infection at the catheter site, bleeding at the catheter site and/or a blocked, leaking, or displaced catheter.
Gastrointestinal side effects frequently include nausea, vomiting, diarrhea, enteritis, and stomatitis. Duodenal ulcer, duodenitis, gastritis, bleeding, gastroenteritis, glossitis, pharyngitis, anorexia, cramps, abdominal pain, possible intra- and extrahepatic biliary sclerosis, and acalculous cholecystitis have also been reported.
Hematologic side effects include anemia, leukopenia, and thrombocytopenia.
Hepatic side effects include elevations of alkaline phosphatase, serum transaminase, serum bilirubin, and lactic dehydrogenase.
Dermatologic side effects include alopecia, dermatitis, nonspecific skin toxicity, and rash.
Cardiovascular side effects include myocardial ischemia and myocardial injury.
General side effects include fever, lethargy, malaise, and weakness.
Laboratory abnormalities include BSP, prothrombin, total proteins, sedimentation rate and thrombocytopenia.
Nervous system side effects include neurotoxicity.
More FUDR resources
- FUDR Prescribing Information (FDA)
- FUDR MedFacts Consumer Leaflet (Wolters Kluwer)
- FUDR Concise Consumer Information (Cerner Multum)
- FUDR Advanced Consumer (Micromedex) - Includes Dosage Information
- Floxuridine Prescribing Information (FDA)
- Floxuridine Professional Patient Advice (Wolters Kluwer)
- Floxuridine Monograph (AHFS DI)
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