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Flurbiprofen ophthalmic Side Effects

For the Consumer

Applies to flurbiprofen ophthalmic: ophthalmic solution

In addition to its needed effects, some unwanted effects may be caused by flurbiprofen ophthalmic. In the event that any of these side effects do occur, they may require medical attention.

You should check with your doctor immediately if any of these side effects occur when taking flurbiprofen ophthalmic:

Incidence not known
  • Eye irritation or redness
  • increased sensitivity of the eyes to light
  • red or bloodshot eye

Some of the side effects that can occur with flurbiprofen ophthalmic may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Incidence not known
  • Stinging or burning of the eye when medicine is applied

For Healthcare Professionals

Applies to flurbiprofen ophthalmic: ophthalmic solution


Ocular side effects have included transient burning, discomfort, or stinging upon instillation in approximately 15% of patients. Local itching or foreign body sensation, fibrosis, miosis, mydriasis, tearing, hyphema, ocular hyperemia, dull pain, photophobia, follicular conjunctivitis, and increased bleeding tendency of ocular tissues with ocular surgery have also been reported. Topical flurbiprofen may slow corneal wound healing. Some data indicate slightly greater postoperative intraocular pressures associated with flurbiprofen relative to placebo.[Ref]


1. "Product Information. Ocufen Liquifilm (flurbiprofen)." Allergan Inc, Irvine, CA.

2. Hersh PS, Rice BA, Baer JC, Wells PA, Lynch SE, McGuigan LJ, Foster CS "Topical nonsteroidal agents and corneal wound healing." Arch Ophthalmol 108 (1990): 577-83

3. Tsuchisaka H, Takase M "Topical flurbiprofen in intraocular surgery on diabetic and nondiabetic patients." Ann Ophthalmol 22 (1990): 15-9,23

4. Lyons CJ, Hakin KN, Watson PG "Topical flurbiprofen: an effective treatment for episcleritis?" Eye 4(Pt 3) (1990): 521-5

Not all side effects for flurbiprofen ophthalmic may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

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