Exondys 51 Side Effects

Generic name: eteplirsen

Medically reviewed by Drugs.com. Last updated on Nov 27, 2023.

Note: This document contains side effect information about eteplirsen. Some dosage forms listed on this page may not apply to the brand name Exondys 51.

Applies to eteplirsen: intravenous solution.

Serious side effects of Exondys 51

Along with its needed effects, eteplirsen (the active ingredient contained in Exondys 51) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor or nurse immediately if any of the following side effects occur while taking eteplirsen:

More common

• Loss of balance control
• vomiting

Other side effects of Exondys 51

Some side effects of eteplirsen may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects.

Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

Incidence not known

• Bleeding, blistering, burning, coldness, discoloration of the skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at the injection site
• blistering, burning, crusting, dryness, or flaking of the skin
• itching, scaling, severe redness, soreness, or swelling of the skin

For Healthcare Professionals

Applies to eteplirsen: intravenous solution.

General

The most commonly reported adverse events were balance disorder and vomiting.^[Ref]

Cardiovascular

Postmarketing reports: Flushing^[Ref]

Dermatologic

Very common (10% or more): Contact dermatitis (25%), rash, urticaria^[Ref]

Gastrointestinal

Very common (10% or more): Vomiting (38%)^[Ref]

Hypersensitivity

Frequency not reported: Hypersensitivity reactions^[Ref]

Local

Very common (10% or more): Catheter site pain

Postmarketing reports: Cyanosis of the lips^[Ref]

Metabolic

Postmarketing reports: Dehydration^[Ref]

Nervous system

Very common (10% or more): Balance disorder (38%), headache^[Ref]

Respiratory

Very common (10% or more): Cough

Postmarketing reports: Bronchospasm^[Ref]

Other

Postmarketing reports: Malaise, pyrexia, protein urine present^[Ref]

Frequently asked questions

• What are the new drugs for Duchenne muscular dystrophy?
• Is Exondys 51 a type of gene therapy?
• Is there a specific age range for which Exondys 51 will work?
• What types of DMD can Exondys 51 be used for?
• How is Exondys 51 administered?

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Some side effects may not be reported. You may report them to the FDA.

Medical Disclaimer