Emcyt Side Effects
Generic Name: estramustine
Note: This document contains side effect information about estramustine. Some of the dosage forms listed on this page may not apply to the brand name Emcyt.
Some side effects of Emcyt may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.
For the Consumer
Applies to estramustine: oral capsule
Along with its needed effects, estramustine (the active ingredient contained in Emcyt) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.
Check with your doctor immediately if any of the following side effects occur while taking estramustine:Rare
- Black, tarry stools
- blood in urine or stools
- cough or hoarseness
- fever or chills
- headaches (severe or sudden)
- loss of coordination (sudden)
- lower back or side pain
- painful or difficult urination
- pains in chest, groin, or leg (especially calf of leg)
- pinpoint red spots on skin
- shortness of breath (sudden, for no apparent reason)
- slurred speech (sudden)
- unusual bleeding or bruising
- vision changes (sudden)
- weakness or numbness in arm or leg
Check with your doctor as soon as possible if any of the following side effects occur while taking estramustine:More common
- Swelling of feet or lower legs
- Skin rash or fever
- unusual tiredness or weakness
Some side effects of estramustine may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:More common
- Breast tenderness or enlargement
- decreased interest in sex
- Trouble in sleeping
For Healthcare Professionals
Applies to estramustine: oral capsule
Gynecomastia and impotence have been reported as estrogenic effects.
Genitourinary side effects including breast tenderness (71%), mild breast enlargement (65%), and moderate breast enlargement (11%) have been reported. One case of hemolytic-uremic syndrome has also been reported.
Hepatic side effects including LDH and/or SGOT abnormalities (33%), bilirubin and SGOT abnormalities (2%), and bilirubin, LDH, and SGOT abnormalities (2%) have been reported.
Exacerbation of preexisting or incipient peripheral edema or congestive heart disease has been reported.
Cardiovascular side effects including edema (20%), leg cramps (9%), myocardial infarction (3%), thrombophlebitis (3%), congestive heart failure (3%), cerebrovascular accident (2%), and pulmonary emboli (2%) have been reported.
Gastrointestinal side effects including nausea (16%), diarrhea (13%), minor gastrointestinal upset (11%), anorexia (4%), and flatulence (2%) have been reported.
Respiratory side effects including dyspnea (12%) have been reported.
Hematologic side effects including leukopenia (4%) have been reported.
Other side effects including lethargy (4%), insomnia (3%), and emotional lability (2%) have been reported.
Dermatologic side effects including easy bruising (3%), pruritus (2%), and dry skin (2%) have been reported.
Oncologic side effects including mutagenicity have been reported for both estradiol and nitrogen mustard. Animal studies on estrogens have reported an increase in the frequency of carcinomas of the breast and liver.
More about Emcyt (estramustine)
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