Elestat Side Effects

Generic Name: epinastine ophthalmic

Note: This page contains information about the side effects of epinastine ophthalmic. Some of the dosage forms included on this document may not apply to the brand name Elestat.

Not all side effects for Elestat may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to epinastine ophthalmic: ophthalmic solution

Along with its needed effects, epinastine ophthalmic (the active ingredient contained in Elestat) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking epinastine ophthalmic:

More common
  • Burning sensation in the eye
  • increase in blood flow to the whites of the eyes
  • redness, itching, pain, swelling, or other irritation of the eye

Some side effects of epinastine ophthalmic may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common - some side effects were similar to problem being treated
  • Body aches or pain
  • chills
  • cough
  • difficulty with breathing
  • ear congestion
  • fever
  • headache
  • loss of voice
  • nasal congestion
  • runny nose
  • sneezing
  • sore throat
  • unusual tiredness or weakness
Less common - some side effects were similar to problem being treated
  • Congestion
  • hoarseness
  • increased cough
  • pain or tenderness around the eyes and cheekbones
  • shortness of breath
  • stuffy nose
  • tender, swollen glands in the neck
  • tightness of the chest or wheezing
  • trouble with swallowing
  • troubled breathing
  • voice changes

For Healthcare Professionals

Applies to epinastine ophthalmic: ophthalmic solution


Ocular side effects have included burning, folliculosis, hyperemia, and pruritus in 1% to 10% of patients. Postmarketing experience has included increased lacrimation.


Respiratory side effects have included cold symptoms and upper respiratory infections in 10% of patients, and headache, rhinitis, sinusitis, and pharyngitis in 1% to 3% of patients; some of which may have been due to the underlying disease.

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