Eflornithine Side Effects

Please note - some side effects for Eflornithine may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).

Side Effects of Eflornithine - for the Consumer

Eflornithine Cream

All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Eflornithine Cream:

Redness; skin tingling; temporary stinging or burning.

Severe allergic reactions (rash; hives; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); bleeding or irritation of the skin.

Side Effects by Body System

General

General side effects have been mild in intensity and resolved without medical treatment or discontinuation of therapy. Two percent of patients discontinued studies with eflornithine topical due to adverse events.

Dermatologic

Dermatological side effects have included acne (10.8% to 21.4%), Pseudofolliculitis barbae (4.9% to 16.3%), stinging skin (4.1% to 7.9%), burning skin (3.5% to 4.3%), dry skin (1.8% to 3.3%), pruritus (3.1% to 4%), erythema (1.3% to 2.5%), tingling skin (2.2% to 3.6%), skin irritation (1% to 1.8%), rash (1.5% to 2.8%), alopecia (1.5% to 2.5%), folliculitis (0.5% to 1%), ingrown hair (0.3% to 2%), and facial edema (0.3% to 3%). Those reported in less than 1% of patients include bleeding skin, cheilitis, contact dermatitis, herpes simplex, numbness, and rosacea.

Nervous system

Nervous system side effects have included headache (3.8% to 5%), dizziness (1.3% to 1.5%), and asthenia (0% to 1%). Numbness has been reported in less than 1% of patients.

Gastrointestinal

Gastrointestinal side effects have included dyspepsia (1.9% to 2.5%), anorexia (0.7% to 2%), nausea (0.5% to 1%), and swelling of lips (<1%).

Local

Local side effects have included transient stinging or burning when applied to abraded or broken skin.

Disclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This information does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug of drug combination is safe, effective, or appropriate for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of information provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.