Dosaflex Side Effects
Generic Name: senna
Note: This page contains information about the side effects of senna. Some of the dosage forms included on this document may not apply to the brand name Dosaflex.
For the Consumer
Applies to senna: oral solution, oral tablets and chewable pieces
Side effects include:
Abdominal discomfort, nausea, mild cramps, griping, faintness.
For Healthcare Professionals
Applies to senna: compounding powder, oral disintegrating strip, oral granule, oral liquid, oral syrup, oral tablet, oral tablet chewable, rectal suppository
Gastrointestinal side effects have included esophageal impaction and duodenal bezoars. These effects have been reported in patients receiving a bulk laxative product containing 82% psyllium and 18% senna (the active ingredient contained in Dosaflex) (commercially available as Perdiem Overnight Relief).[Ref]
Hypersensitivity side effects have rarely included occupational sensitization to senna (the active ingredient contained in Dosaflex) [Ref]
One case has been reported involving a factory worker who developed IgE-mediated asthma and rhinoconjunctivitis five months after exposure to senna.[Ref]
Musculoskeletal side effects have rarely included finger clubbing.[Ref]
1. "Product Information. Perdiem Overnight Relief (psyllium)" Novartis Pharmaceuticals, East Hanover, NJ.
2. Helin T, Makinen-Kiljunen S "Occupational asthma and rhinoconjunctivitis caused by senna." Allergy 51 (1996): 181-4
3. Malmquist J, Ericsson B, Hulten-Nosslin MB, Jeppsson JO, Ljungberg O "Finger clubbing and aspartylglucosamine excretion in a laxative- abusing patient." Postgrad Med J 56 (1980): 862-4
4. Prior J, White I "Tetany and clubbing in patient who ingested large quantities of senna [letter." Lancet 2 (1978): 947
Not all side effects for Dosaflex may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
More about Dosaflex (senna)
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