Senna Pregnancy and Breastfeeding Warnings
Senna is also known as: Agoral, Black Draught, Dosaflex, Dr Caldwell Laxative, Ex-Lax, Ex-Lax Chocolated, Ex-Lax Gentle Nature, Ex-Lax Maximum Relief Formula, Ex-Lax Regular Strength Pills, Fletchers Castoria, Gentlax, Innerclean, Little Tummys Laxative Drops, Pedia-Lax Quick Dissolve Strips, Perdiem Overnight, Senexon, Senna Concentrate, Senna Lax, Senna-gen, Senokot, Senokot Child, Senokot To Go, Senolax, Uni-Cenna, X-Prep
Senna Pregnancy Warnings
Senna has been assigned to pregnancy category C by the FDA. Animal studies have failed to reveal evidence of teratogenicity. There are no controlled data in human pregnancy. Senna should only be given during pregnancy when benefits outweigh risks.
Senna Breastfeeding Warnings
Senna is not excreted into human milk. However, senna is a prodrug which is metabolized in vivo to the active sennosides (glucosides of rhein). Rhein is excreted into human milk in very small amounts. No adverse effects have been observed in nursing infants. The American Academy of Pediatrics considers senna to be compatible with breast-feeding.
References for pregnancy information
- Briggs GG, Freeman RK, Yaffe SJ.. "Drugs in Pregnancy and Lactation. 5th ed." Baltimore, MD: Williams & Wilkins (1998):
References for breastfeeding information
- Greenhalf JO, Leonard HS "Laxatives in the treatment of constipation in pregnant and breastfeeding mothers." Practitioner 210 (1973): 259-63
- Shepard TH. "Catalog of Teratogenic Agents 6th" Baltimore, MD: Johns Hopkins University Press (1989): 574-5
- Werthmann ME, Kres SV "Quantitative excretion of senokot in human breast milk." Med Ann Dist Columbia 42 (1973): 4-5
Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Wolters Kluwer Health and Drugs.com is accurate, up-to-date and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This material does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or combination thereof in no way should be construed to indicate that the drug or combination is safe, effective, or appropriate for any given patient. Multum Information Services, Inc. does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. Copyright 2000-2008 Multum Information Services, Inc. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.