Denavir Side Effects

Generic Name: penciclovir topical

Note: This page contains information about the side effects of penciclovir topical. Some of the dosage forms included on this document may not apply to the brand name Denavir.

Not all side effects for Denavir may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to penciclovir topical: topical cream

In addition to its needed effects, some unwanted effects may be caused by penciclovir topical (the active ingredient contained in Denavir). In the event that any of these side effects do occur, they may require medical attention.

If any of the following side effects occur while taking penciclovir topical, check with your doctor or nurse as soon as possible:

Rare
  • Mild pain, burning, or stinging

Some of the side effects that can occur with penciclovir topical may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common
  • Headache
Less common
  • Change in sense of taste
  • decreased sensitivity of skin, particularly to touch
  • redness of the skin
  • skin rash

For Healthcare Professionals

Applies to penciclovir topical: topical cream

General

In clinical trials, 1 or more local side effects were reported by 3% of patients using penciclovir topical (the active ingredient contained in Denavir) and 4% of patients using placebo.

Dermatologic

Common (1% to 10%): Application site reaction (1%)
Uncommon (0.1% to 1%): Hypesthesia/local anesthesia (less than 1%), erythematous rash (less than 1%)
Frequency not reported: Mild erythema
Postmarketing reports: Local edema, pain, paresthesia, pruritus, skin discoloration, urticaria, aggravated condition, decreased therapeutic response

Other

Uncommon (0.1% to 1%): Taste perversion (less than 1%)
Postmarketing reports: Oral/pharyngeal edema, parosmia

Nervous system

Postmarketing reports: Headache

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