Corque Side Effects

Generic Name: clioquinol / hydrocortisone topical

Note: This page contains information about the side effects of clioquinol / hydrocortisone topical. Some of the dosage forms included on this document may not apply to the brand name Corque.

Not all side effects for Corque may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to clioquinol / hydrocortisone topical: topical cream, topical ointment

In addition to its needed effects, some unwanted effects may be caused by clioquinol / hydrocortisone topical. In the event that any of these side effects do occur, they may require medical attention.

You should check with your doctor immediately if any of these side effects occur when taking clioquinol / hydrocortisone topical:

Incidence not known
  • Blistering, burning, crusting, dryness, or flaking of the skin
  • burning and itching of the skin with pinhead-sized red blisters
  • burning, itching, and pain in hairy areas, or pus at the root of the hair
  • darkening of the skin
  • diarrhea
  • dizziness
  • dryness
  • fainting
  • fast heartbeat
  • fever
  • hives, itching, or rash
  • hoarseness
  • irritation
  • itching, scaling, severe redness, soreness, or swelling of the skin
  • joint pain, stiffness, or swelling
  • loss of appetite
  • mental depression
  • nausea
  • reddish purple lines on the arms, face, legs, trunk, or groin
  • redness and scaling around the mouth
  • softening of the skin
  • swelling of the eyelids, face, lips, hands, or feet
  • thinning of the skin with easy bruising, especially when used on the face or where the skin folds together (eg, between the fingers)
  • tightness in the chest
  • troubled breathing or swallowing
  • unusual tiredness or weakness
  • vomiting

Some of the side effects that can occur with clioquinol / hydrocortisone topical may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Incidence not known
  • Acne or pimples
  • increased hair growth on the forehead, back, arms, and legs
  • lightening of normal skin color
  • lightening of the treated areas of dark skin

For Healthcare Professionals

Applies to clioquinol / hydrocortisone topical: topical cream, topical kit, topical ointment

Dermatologic

Burning; itching; irritation; dryness; folliculitis; blistering, peeling, redness, swelling; hypertrichosis; acneiform eruptions; hypopigmentation; perioral dermatitis; maceration of the skin, secondary infection; skin atrophy; striae; and miliaria or other signs of irritation not present before therapy have been reported with topical corticosteroids and clioquinol, especially under occlusive dressings.[Ref]

Rare (less than 0.1%): Discoloration (yellowing) of hair and nails, irritating to sensitized skin
Frequency not reported: Rash; thinning of the skin with easy bruising; itching; burning; irritation; dryness; hypopigmentation; acneiform eruptions; skin atrophy; folliculitis; blistering, peeling, redness, swelling; hypertrichosis; perioral dermatitis; maceration of the skin, secondary infection; striae; miliaria or other signs of irritation not present before therapy[Ref]

Hypersensitivity

Allergic contact dermatitis has been reported with topical corticosteroids and clioquinol, especially under occlusive dressings.[Ref]

Frequency not reported: Hypersensitivity, allergic contact dermatitis[Ref]

Endocrine

Clioquinol:
Frequency not reported: Interference with thyroid function tests, significant elevation of protein-bound iodine or butanol-extractable iodine, decrease in radioactive iodine uptake

Topical corticosteroids (systemic absorption):
Frequency not reported: Reversible hypothalamic-pituitary-adrenal axis suppression, manifestations of Cushing's syndrome[Ref]

Metabolic

Topical corticosteroids (systemic absorption):
Frequency not reported: Hyperglycemia[Ref]

Genitourinary

Topical corticosteroids (systemic absorption):
Frequency not reported: Glucosuria[Ref]

References

1. "Product Information. Clioquinol-Hydrocortisone (clioquinol-hydrocortisone topical)." Allscripts Pharmaceutical Company, Vernon Hills, IL.

More about Corque (clioquinol / hydrocortisone topical)

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