Colazal Side Effects
Please note - some side effects for Colazal may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA at http://www.fda.gov/medwatch/ or 1-800-FDA-1088 (1-800-332-1088).
Side Effects of Colazal - for the Consumer
Colazal
All medicines may cause side effects, but many people have no, or minor, side effects. Check with your doctor if any of these most COMMON side effects persist or become bothersome when using Colazal:
Seek medical attention right away if any of these SEVERE side effects occur when using Colazal:Diarrhea; headache; heartburn; joint or muscle pain; loss of appetite; nausea; runny or stuffy nose; stomach pain; vomiting.
TopSevere allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); dark urine; fatigue; fever; rectal bleeding; signs of infection (eg, chills or persistent sore throat); yellowing of the skin or eyes.
Side Effects by Body System
Gastrointestinal
Gastrointestinal side effects have included upper abdominal pain (13%), abdominal pain (6% to 12%), diarrhea (5% to 9%), vomiting (4% to 10%), colitis ulcerative (6%), nausea (4% to 5%), hematochezia (4%), stomatitis (3%), dyspepsia (2%), flatulence (2%), cramps (1%), frequent stools (1%), dry mouth (1%), and constipation (1%). Pancreatitis has been reported during postmarketing experience.
Musculoskeletal
Musculoskeletal side effects have included arthralgia (4%), myalgia (1%), and cramps (1%).
Respiratory
Respiratory side effects have included nasopharyngitis (6%), influenza (4%), respiratory tract infection (4%), coughing (2% to 3%), pharyngolaryngeal pain (3%), pharyngitis (2%), and rhinitis (2%). Pleural effusion, pneumonia (with and without eosinophilia), and alveolitis have been reported during postmarketing experience.
Nervous system
Nervous system side effects have included headache (8% to 15%), insomnia (2%), and dizziness (1%).
Hepatic
Hepatic side effects have included elevated liver enzymes, jaundice, cholestatic jaundice, cirrhosis, and hepatocellular damage. Liver necrosis and liver failure have been reported in postmarketing clinical trials, although no causal relationship has been established. Hepatotoxicity, including elevated liver function tests (SGOT/AST, SGPT/ALT, GGT, LDH, alkaline phosphatase, bilirubin), jaundice, cholestatic jaundice, cirrhosis, hepatocellular damage including liver necrosis, and liver failure have been reported during the postmarketing of products that contain (or are metabolized to) mesalamine. One case of Kawasaki-like syndrome, which included hepatic function changes, has been reported.
Hematologic
Hematologic side effects have included thrombocythemia, anemia, and prothrombin changes.
Cardiovascular
Cardiovascular side effects have included hypertension, palpitations, bradycardia, and pericarditis. Myocarditis and vasculitis have been reported during postmarketing experience.
Other
Other side effects have included headache (8% to 15%), pyrexia (6%), fatigue (2% to 4%), fever (2%), anorexia (2%), and flu-like syndrome (1%).
Genitourinary
Genitourinary side effects have included dysmenorrhea (3%).
Dermatologic
Dermatologic side effects have included pruritus and several cases of alopecia during postmarketing experience.
TopDisclaimer: Every effort has been made to ensure that the information provided is accurate, up-to-date, and complete, but no guarantee is made to that effect. In addition, the drug information contained herein may be time sensitive and should not be utilized as a reference resource beyond the date hereof. This information does not endorse drugs, diagnose patients, or recommend therapy. This drug information is a reference resource designed as supplement to, and not a substitute for, the expertise, skill , knowledge, and judgement of healthcare practitioners in patient care. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug of drug combination is safe, effective, or appropriate for any given patient. Drugs.com does not assume any responsibility for any aspect of healthcare administered with the aid of information provided. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse, or pharmacist.
