Codituss DM Side Effects
Generic Name: dextromethorphan / phenylephrine / pyrilamine
Note: This page contains information about the side effects of dextromethorphan / phenylephrine / pyrilamine. Some of the dosage forms included on this document may not apply to the brand name Codituss DM.
Not all side effects for Codituss DM may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
For the Consumer
Applies to dextromethorphan / phenylephrine / pyrilamine: chewable tablets
Other dosage forms:
Check with your doctor if any of these most COMMON side effects persist or become bothersome:
Seek medical attention right away if any of these SEVERE side effects occur while taking dextromethorphan / phenylephrine / pyrilamine:
Constipation; diarrhea; dizziness; drowsiness; excitability; headache; loss of appetite; nausea; nervousness or anxiety; upset stomach; vomiting; weakness.
Severe allergic reactions (rash; hives; itching; difficulty breathing; tightness in the chest; swelling of the mouth, face, lips, or tongue); difficulty urinating or inability to urinate; fast or irregular heartbeat; hallucinations; seizures; severe dizziness, lightheadedness, or headache; tremor; trouble sleeping; vision changes.
For Healthcare Professionals
Applies to dextromethorphan / phenylephrine / pyrilamine: oral liquid, oral suspension, oral suspension extended release, oral syrup, oral tablet chewable, oral tablet chewable extended release
Cardiovascular side effects including arrhythmias, hypertension, hypotension, and palpitations have been reported.[Ref]
Nervous system side effects including coordination disturbances, drowsiness, dysphoria, euphoria, headache, insomnia, irritability, nervousness, sedation, and seizures have been reported.[Ref]
Dermatologic side effects including photosensitivity, pruritus, rash, and urticaria have been reported.[Ref]
Gastrointestinal side effects including constipation, diarrhea, epigastric discomfort, nausea, vomiting, and xerostomia have been reported.[Ref]
Genitourinary side effects including difficult urination and urinary frequency have been reported.[Ref]
Hematologic side effects including agranulocytosis, hemolytic anemia, and thrombocytopenia have been reported.[Ref]
Neuromuscular side effects including tremor and weakness have been reported.[Ref]
Ocular side effects including visual disturbances have been reported.[Ref]
Respiratory side effects including shortness of breath and wheezing have been reported.[Ref]
1. "Product Information. Codal-DM Syrup (dextromethorphan / phenylephrine / pyrilamine)." Cypress Pharmaceutical Inc, Madison, MS.
2. "Product Information. Viravan-DM (dextromethorphan / phenylephrine / pyrilamine)." PediaMed Pharmaceuticals Inc, Exton, PA.
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