Clenz-Lyte Side Effects

Generic Name: polyethylene glycol 3350 with electrolytes

Note: This page contains information about the side effects of polyethylene glycol 3350 with electrolytes. Some of the dosage forms included on this document may not apply to the brand name Clenz-Lyte.

Not all side effects for Clenz-Lyte may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to polyethylene glycol 3350 with electrolytes: oral powder for solution

Along with its needed effects, polyethylene glycol 3350 with electrolytes (the active ingredient contained in Clenz-Lyte) may cause some unwanted effects. Although not all of these side effects may occur, if they do occur they may need medical attention.

Check with your doctor immediately if any of the following side effects occur while taking polyethylene glycol 3350 with electrolytes:

More common
  • Full or bloated feeling
  • pain in the upper stomach
  • pressure in the stomach
  • stomach pain
  • swelling of abdominal or stomach area
  • vomiting
Rare
  • Coma
  • confusion
  • convulsions
  • decreased urine output
  • dizziness
  • dry mouth
  • fast or irregular heartbeat
  • headache
  • increased thirst
  • loss of appetite
  • muscle pain or cramps
  • numbness or tingling in the hands, feet, fingertips, lips, or mouth
  • shortness of breath
  • swelling of the face, ankles, or hands
  • unusual tiredness or weakness

Some side effects of polyethylene glycol 3350 with electrolytes may occur that usually do not need medical attention. These side effects may go away during treatment as your body adjusts to the medicine. Also, your health care professional may be able to tell you about ways to prevent or reduce some of these side effects. Check with your health care professional if any of the following side effects continue or are bothersome or if you have any questions about them:

More common
  • Burning, itching, or pain around the anus
  • difficulty with sleeping
  • feeling unusually cold
  • general feeling of discomfort or illness
  • hunger
  • nausea
  • shivering
  • thirst
Less common
  • Acid or sour stomach
  • belching
  • heartburn
  • indigestion
  • stomach discomfort or upset

For Healthcare Professionals

Applies to polyethylene glycol 3350 with electrolytes: oral kit, oral powder for reconstitution

Gastrointestinal

Mallory-Weiss tears are quite rare. In one study it occurred in only 0.06% of over 3,000 patients.

Complete rectal prolapse was reported in a 71-year-old who had been given 4 L of PEG-ELS. The patient was observed for 2 days and had no recurrence of the prolapse.

Gastrointestinal side effects have included nausea, vomiting, gas, bloating, complaints of bad taste, anal irritation, and abdominal discomfort. A small percentage of patients who received PEG-ELS have reportedly experienced Mallory-Weiss tears of the esophagus and esophageal perforation. In addition, at least one case of rectal prolapse has been reported.

Cardiovascular

Cardiac arrhythmias, especially increased ventricular ectopy, have been associated with PEG-ELS use.

Cardiovascular side effects have included arrhythmias.

Hypersensitivity

Hypersensitivity side effects have rarely included anaphylaxis. Rash, urticaria, lip and facial swelling, dyspnea, chest tightness, and throat tightness have been reported during postmarketing experience.

A 70-year-old male developed shortness of breath, wheezing, skin flushing, and lowered blood pressure after drinking a second glass of PEG-ELS.

Dermatologic

Dermatologic side effects have rarely included urticaria.

More about Clenz-Lyte (polyethylene glycol 3350 with electrolytes)

Consumer resources

Professional resources

Related treatment guides

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