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Calcitrene Side Effects

Generic Name: calcipotriene topical

Note: This page contains information about the side effects of calcipotriene topical. Some of the dosage forms included on this document may not apply to the brand name Calcitrene.

Not all side effects for Calcitrene may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to calcipotriene topical: topical cream, topical foam, topical ointment, topical solution

In addition to its needed effects, some unwanted effects may be caused by calcipotriene topical (the active ingredient contained in Calcitrene). In the event that any of these side effects do occur, they may require medical attention.

You should check with your doctor immediately if any of these side effects occur when taking calcipotriene topical:

More common
  • Skin redness, swelling, or itching
  • skin rash
  • worsening of psoriasis

Some of the side effects that can occur with calcipotriene topical may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

More common
  • Burning, dryness, irritation, peeling, or redness of the skin
Less common
  • Pain at the application site
Less common or rare
  • Darker color in the treated areas of the skin
  • pus in the hair follicles

For Healthcare Professionals

Applies to calcipotriene topical: topical cream, topical foam, topical ointment, topical solution

General

The most commonly reported side effects were burning, stinging, tingling, and skin irritation.[Ref]

Hypersensitivity

Very rare (less than 0.01%): Allergic reactions (including angioedema)[Ref]

Dermatologic

Very common (10% or more): Transient burning (about 23%), stinging (about 23%), tingling (about 23%), skin irritation (up to 15%), rash (11%)
Common (1% to 10%): Pruritus, dermatitis, contact dermatitis (including facial and perioral), dry skin, irritation, worsening of psoriasis, erythema, peeling
Uncommon (0.1% to 1%): Skin atrophy, hyperpigmentation, folliculitis, eczema
Frequency not reported: Transient changes in skin pigmentation, transient photosensitivity, urticaria, angioedema, skin exfoliation[Ref]

Metabolic

Uncommon (0.1% to 1%): Hypercalcemia
Rare (less than 0.1%): Transient increases in serum calcium
Very rare (less than 0.01%): Hypercalcemia, hypercalciuria (especially if the total recommended dose is exceeded)[Ref]

Local

Very common (10% or more): Lesional/perilesional irritation (up to 39%), face and/or scalp irritation (up to 25%)[Ref]

Other

Frequency not reported: Periorbital or face edema[Ref]

References

1. "Product Information. Dovonex (calcipotriene)." Westwood Squibb Pharmaceutical Corporation, Eatontown, NJ.

2. Cerner Multum, Inc. "Australian Product Information." O 0

3. Cerner Multum, Inc. "UK Summary of Product Characteristics." O 0

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