BeneFix Side Effects

Generic Name: coagulation factor ix

Note: This page contains information about the side effects of coagulation factor ix. Some of the dosage forms included on this document may not apply to the brand name BeneFix.

Not all side effects for BeneFix may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

For the Consumer

Applies to coagulation factor ix: parenteral powder for infusion

Side effects include:

Headache, dizziness, rash, hives, injection site reactions/pain, nausea.

For Healthcare Professionals

Applies to coagulation factor ix: intravenous kit, intravenous powder for injection


Hypersensitivity side effects have included hypersensitivity reactions, including bronchospastic reactions and/or hypotension and anaphylaxis.


Hematologic side effects have included and the development of high-titer inhibitors necessitating alternative treatments to factor IX replacement therapy.


Gastrointestinal side effects have included nausea and vomiting.


Dermatologic side effects have included hives, rash, and flushing.


Local side effects have included Injection site reaction, Injection site pain, cellulitis at IV site, and phlebitis at IV site.

Nervous system

Nervous system side effects have included headache, dizziness, taste perversion (altered taste), shaking, and drowsiness.


Respiratory side effects have included dry cough, hypoxia, chest tightness, and dyspnea (respiratory distress)


General side effects have included fever.


Ocular side effects have included blurred vision.


Renal side effects have e included renal infarction.

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