Bactroban Side Effects
Generic Name: mupirocin topical
Note: This page contains information about the side effects of mupirocin topical. Some of the dosage forms included on this document may not apply to the brand name Bactroban.
Not all side effects for Bactroban may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.
For the Consumer
Applies to mupirocin topical: topical cream, topical ointment
Other dosage forms:
In addition to its needed effects, some unwanted effects may be caused by mupirocin topical (the active ingredient contained in Bactroban). In the event that any of these side effects do occur, they may require medical attention.
Some of the side effects that can occur with mupirocin topical may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:Less common
- Dry skin
- skin burning, itching, pain, rash, redness, stinging, or swelling
- Abdominal pain
- secondary wound infection
- sores on mouth and on lips
For Healthcare Professionals
Applies to mupirocin topical: compounding powder, nasal ointment, topical cream, topical kit, topical ointment
Local adverse effects may be associated with mupirocin application. Mupirocin ointment or cream may commonly cause itching, pain, stinging, and burning. Local effects from the nasal formulation have included epistaxis, rhinitis, taste perversion, pharyngitis, burning, and cough.[Ref]
Mupirocin ointment in a polyethylene glycol base has previously (prior to the release of a nasal formulation) been used intranasally. Common side effects associated with such use, which may be related to the polyethylene glycol, include nasal congestion, dryness, burning or irritation and unpleasant taste.[Ref]
Gastrointestinal side effects have included nausea (1.1%), abdominal pain (<1%), and diarrhea (<1%). Dry mouth has been reported with mupirocin nasal (<1%).[Ref]
Hypersensitivity reactions have infrequently included allergic contact dermatitis.[Ref]
Nervous system side effects associated with intranasal mupirocin have included headache (9%). Dizziness has been reported with mupirocin ointment (<1%).[Ref]
Ocular side effects associated with mupirocin nasal ointment have included blepharitis (<1%).[Ref]
Dermatologic side effects associated with mupirocin ointment or cream have included pain and bleeding secondary to eczema, cellulitis, dermatitis, increased exudate, secondary wound infection, hives, and rash.[Ref]
1. Parenti MA, Hatfield SM, Leyden JJ "Mupirocin: a topical antibiotic with a unique structure and mechanism of action." Clin Pharm 6 (1987): 761-70
2. Rice TD, Duggan AK, DeAngelis C "Cost-effectiveness of erythromycin versus mupirocin for the treatment of impetigo in children." Pediatrics 89 (1992): 210-4
3. "Product Information. Bactroban (mupirocin)." SmithKline Beecham, Philadelphia, PA.
4. Rumsfield J, West DP, Aronson IK "Topical mupirocin in the treatment of bacterial skin infections." Drug Intell Clin Pharm 20 (1986): 943-8
5. Scully BE, Briones F, Gu JW, Neu HC "Mupirocin treatment of nasal staphylococcal colonization." Arch Intern Med 152 (1992): 353-6
6. Infectious Diseases and Immunization Committtee, Canadian Paediatric Society "Mupirocin in the treatment of impetigo." Can Med Assoc J 142 (1990): 543-4
7. Eedy DJ "Mupirocin allergy in the setting of venous ulceration." Contact Dermatitis 32 (1995): 240-1
8. Ward A, Campoli-Richards DM "Mupirocin. A review of its antibacterial activity, pharmacokinetic properties and therapeutic use." Drugs 32 (1986): 425-44
9. Zappi EG, Brancaccio RR "Allergic contact dermatitis from mupirocin ointment." J Am Acad Dermatol 36 (1997): 266
More about Bactroban (mupirocin topical)
- Bactroban cream
- Bactroban ointment
- Bactroban Nasal (Advanced Reading)
- Bactroban Topical (Advanced Reading)
- Other brands: Centany
Related treatment guides
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