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AN-DTPA Side Effects

Generic Name: pentetate calcium trisodium

Note: This page contains information about the side effects of pentetate calcium trisodium. Some of the dosage forms included on this document may not apply to the brand name AN-DTPA.

For the Consumer

Applies to pentetate calcium trisodium: solution

In addition to its needed effects, some unwanted effects may be caused by pentetate calcium trisodium (the active ingredient contained in AN-DTPA). In the event that any of these side effects do occur, they may require medical attention.

Also, because of the way these medicines act on the body, there is a chance that they might cause other unwanted effects that may not occur until months or years after the medicine is used. These may include certain types of cancer, such as leukemia or bladder cancer. Discuss these possible effects with your doctor.

Severity: Major

You should check with your doctor immediately if any of these side effects occur when taking pentetate calcium trisodium:

Incidence unknown
  • Chest pain
  • cough
  • difficulty swallowing
  • dizziness
  • fast heartbeat
  • hives
  • itching
  • puffiness or swelling of the eyelids or around the eyes, face, lips or tongue
  • shortness of breath
  • skin rash
  • tightness in chest
  • unusual tiredness or weakness
  • wheezing

Severity: Minor

Some of the side effects that can occur with pentetate calcium trisodium may not need medical attention. As your body adjusts to the medicine during treatment these side effects may go away. Your health care professional may also be able to tell you about ways to reduce or prevent some of these side effects. If any of the following side effects continue, are bothersome or if you have any questions about them, check with your health care professional:

Incidence unknown
  • Bleeding, blistering, burning, coldness, discoloration of skin, feeling of pressure, hives, infection, inflammation, itching, lumps, numbness, pain, rash, redness, scarring, soreness, stinging, swelling, tenderness, tingling, ulceration, or warmth at site
  • blistering, crusting, irritation, itching, or reddening of skin
  • cracked, dry, scaly skin
  • diarrhea
  • headache
  • lightheadedness
  • metallic taste
  • nausea
  • swelling

For Healthcare Professionals

Applies to pentetate calcium trisodium: injectable solution


Metabolic side effects have included the loss of zinc, magnesium, and manganese from the small intestine, skeleton, panaceas, and testes. Depletion of these endogenous metals can interfere with necessary mitotic cellular processes.[Ref]


Cardiovascular side effects have included chest pain and lightheadedness.[Ref]


Dermatologic side effects have included dermatitis.[Ref]

Nervous system

Nervous system side effects have included headache.[Ref]


Hypersensitivity side effects have included allergic reactions.[Ref]


Local side effects have included injection site reactions.[Ref]


Gastrointestinal side effects have included nausea, diarrhea, and metallic taste.[Ref]


Respiratory side effects have included cough and wheezing.[Ref]


1. "Product Information. Pentetate Calcium Trisodium (pentetate calcium trisodium)." Akorn Inc, Buffalo Grove, IL.

Not all side effects for AN-DTPA may be reported. You should always consult a doctor or healthcare professional for medical advice. Side effects can be reported to the FDA here.

More about AN-DTPA (pentetate calcium trisodium)

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