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Doxazosin Pregnancy and Breastfeeding Warnings

Doxazosin is also known as: Cardura, Cardura XL, Carduran, Cascor, Doxadura

Doxazosin Pregnancy Warnings

Doxazosin has been assigned to pregnancy category C by the FDA. Animal studies have shown that the drug crosses the placenta and that there is decreased fetal survival when rabbits were given 300 times the maximum recommended human dose. Animal studies have failed to reveal evidence of fetal harm after doses 154 and 75 times the maximum recommended human dose were given to pregnant rabbits and rats, respectively. Because animal reproductive studies are not always predictive of human response, doxazosin should be used in pregnancy when there are no alternatives and benefit outweighs risk.

Doxazosin Breastfeeding Warnings

There are no data on the excretion of doxazosin into human milk. Because many drugs are excreted in human milk, caution should be exercised when doxazosin is administered to a nursing mother.

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