Carboprost Pregnancy and Breast Feeding Warnings

Carboprost is also known as: Hemabate

Carboprost Pregnancy Warnings

Carboprost has been assigned to pregnancy category C by the FDA. Animal studies have revealed evidence of embryotoxicity. Furthermore, any dose which produces increased uterine tone could put the embryo or fetus at risk. There are no controlled data in human pregnancy. Carboprost should only be given during pregnancy when benefits outweigh risks.

Carboprost marketed as Hemabate contains benzyl alcohol. Benzyl alcohol has been associated with a fatal "Gasping Syndrome" in premature infants. Animal studies have reported that prostaglandins of the E and F series can induce proliferation of bone. Such effects have also been reported in newborn infants who have received prostaglandin E1 during prolonged treatment.

Carboprost Lactation Warnings

There are no data on the excretion of carboprost into human milk.

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