Benzoyl peroxide / clindamycin topical Pregnancy and Breastfeeding Warnings

Brand names: Acanya, Benzaclin, Duac, Neuac, Onexton, Z-Clinz 10, Z-Clinz 5

Medically reviewed by Drugs.com. Last updated on Jul 31, 2023.

Benzoyl peroxide / clindamycin topical Pregnancy Warnings

This drug should be used during pregnancy only if the potential benefit outweighs the potential risk to the fetus.

AU TGA pregnancy category: A
US FDA pregnancy category: C

Animal studies have not been reported. Developmental toxicity studies when clindamycin was given orally or subcutaneously failed to reveal evidence of teratogenicity. There are no controlled data in human pregnancy.

AU TGA pregnancy category A: Drugs which have been taken by a large number of pregnant women and women of childbearing age without any proven increase in the frequency of malformations or other direct or indirect harmful effects on the fetus having been observed.

US FDA pregnancy category C: Animal reproduction studies have shown an adverse effect on the fetus and there are no adequate and well-controlled studies in humans, but potential benefits may warrant use of the drug in pregnant women despite potential risks.

See references

Benzoyl peroxide / clindamycin topical Breastfeeding Warnings

A decision should be made to discontinue breastfeeding or discontinue the drug, taking into account the importance of the drug to the mother.

Excreted into human milk: Unknown
Excreted into animal milk: Data not available

Comments:
-Orally and parenterally administered clindamycin have appeared in breast milk.
-The infant's skin should not come into direct contact with the areas of skin that have been treated.
-Only water-miscible creams or gels should be applied to the breast because ointments may expose the infant to high levels of mineral paraffins via licking.

See references

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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