Skip to main content

Eli Lilly Says Its New Weight-Loss Drug, Zepbound, Is Now Available

Medically reviewed by Carmen Pope, BPharm. Last updated on Dec 7, 2023.

By Physician’s Briefing Staff HealthDay Reporter

WEDNESDAY, Dec. 6, 2023 -- Eli Lilly has announced that its newly approved weight-loss medication, Zepbound, is now available for patients to take.

"Today opens another chapter for adults living with obesity who have been looking for a new treatment option like Zepbound," Rhonda Pacheco, group vice president of Lilly Diabetes and Obesity, U.S., said in a company news release. "The availability of Zepbound in U.S. pharmacies is the first step, but we have to work hand-in-hand with employers, government, and health care industry partners to remove barriers and make Zepbound available to those who need it."

It was only last month when the U.S. Food and Drug Administration approved Zepbound as a weight-loss medication. Tirzepatide, the active ingredient in Zepbound, had already been approved by the FDA as a treatment for type 2 diabetes under the name Mounjaro.

To trigger weight loss, tirzepatide mimics two hormones, glucagon-like peptide-1 (GLP-1) and glucose-dependent insulinotropic polypeptide. The Novo Nordisk weight-loss medication, Wegovy, uses semaglutide, which only focuses on GLP-1. That difference translated to greater weight loss with Zepbound than Wegovy, a recent study showed. Zepbound has been found to prompt up to a 20.9 percent drop in weight at higher doses, while Wegovy patients typically see a 15 percent reduction in weight.

According to the FDA, the most common side effects of Zepbound include nausea, vomiting, constipation, and diarrhea. The drug's label will also have warnings about the potential for inflammation of the pancreas, gallbladder problems, low blood sugar, acute kidney injury, damage to the retina in people with type 2 diabetes, and suicidal behavior or thinking.

More Information

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2024 HealthDay. All rights reserved.

Read this next

Text Messages + Financial Incentives Boost Weight Loss at 12 Months

WEDNESDAY, May 15, 2024 -- Among men with obesity, an intervention with text messaging plus financial incentive significantly improves weight loss compared with a control group...

GLP-1 Receptor Agonist Use Increases Likelihood of Antidepressant Prescription

WEDNESDAY, May 15, 2024 -- Individuals taking glucagon-like peptide (GLP)-1 receptor agonists have a greater risk for subsequently being dispensed antidepressants, according to a...

Four in 10 Adults With Diabetes Report Taking a GLP-1 Receptor Agonist

TUESDAY, May 14, 2024 -- One in eight adults (12 percent) say they have ever taken a glucagon-like peptide-1 receptor agonist (GLP-1 RA) and 6 percent say they are currently using...

More news resources

Subscribe to our newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.