Skip to main content

Deep-Learning Model Based on Chest X-Ray Helps Predict MACE

Medically reviewed by Carmen Pope, BPharm. Last updated on March 26, 2024.

By Elana Gotkine HealthDay Reporter

TUESDAY, March 26, 2024 -- A deep-learning model based on a chest radiograph (CXR) for cardiovascular disease (CVD) risk (CXR CVD-Risk) predicts major adverse cardiovascular events (MACE) beyond the clinical standard, according to a study published online March 26 in the Annals of Internal Medicine.

Jakob Weiss, M.D., from Massachusetts General Hospital and Harvard Medical School in Boston, and colleagues developed and tested CXR CVD-Risk, which estimates 10-year risk for MACE from routine CXR, and compared the performance to that of the traditional atherosclerotic CVD (ASCVD) risk score. The CXR CVD-Risk model was developed using data from a cancer screening trial and was externally validated in 8,869 outpatients with unknown ASCVD risk and 2,132 outpatients with known ASCVD risk.

The researchers found that after adjustment for risk factors, the 10-year risk for MACE was higher for those with a risk of 7.5 percent or higher as predicted by CXR CVD-Risk among 8,869 outpatients with unknown ASCVD risk (adjusted hazard ratio, 1.73). CXR CVD-Risk predicted MACE beyond the traditional ASCVD risk score in the additional 2,132 outpatients with known ASCVD risk (adjusted hazard ratio, 1.88).

"Opportunistic screening of CXRs may help identify individuals at high risk for cardiovascular disease, prompting risk factor assessment and targeted prevention," the authors write.

Abstract/Full Text (subscription or payment may be required)

Disclaimer: Statistical data in medical articles provide general trends and do not pertain to individuals. Individual factors can vary greatly. Always seek personalized medical advice for individual healthcare decisions.

© 2024 HealthDay. All rights reserved.

Posted March 2024

Read this next

Fish Oil Beneficial for Reducing Risk for Cardiovascular Disease Progression

WEDNESDAY, May 22, 2024 -- The role of regular use of fish oil supplements varies for people with and without cardiovascular disease, according to a study published online May 21...

Ultraprocessed Foods Increase Adiposity, Cardiometabolic Risk in Children

WEDNESDAY, May 22, 2024 -- High ultraprocessed food (UPF) consumption in young children is associated with adiposity and other cardiometabolic risk factors, according to a study...

Physical Activity Time, Step Counts Yield Similar Results

TUESDAY, May 21, 2024 -- Moderate-to-vigorous physical activity (MVPA) time and step counts are similarly associated with all-cause mortality and cardiovascular disease, according...

More news resources

Subscribe to our newsletter

Whatever your topic of interest, subscribe to our newsletters to get the best of Drugs.com in your inbox.