Generic name: aflibercept ophthalmic [ a-FLIB-er-sept-off-THAL-mik ]
Brand names: Eylea, Eylea HD, Eylea Pre-filled Syringe
Drug class: Anti-angiogenic ophthalmic agents

Medically reviewed by Drugs.com on Jan 19, 2024. Written by Cerner Multum.

What is Eylea Pre-filled Syringe?

Eylea Pre-filled Syringe (for the eyes) is used in adults to treat wet age-related macular degeneration, and macular edema following retinal vein occlusion.

Eylea Pre-filled Syringe is also used in adults to treat diabetic retinopathy, diabetic macular edema, and retinopathy of prematurity in premature babies.

Eylea Pre-filled Syringe may also be used for purposes not listed in this medication guide.

Eylea Pre-filled Syringe side effects

Get emergency medical help if you have signs of an allergic reaction: hives, difficult breathing, swelling of your face, lips, tongue, or throat.

Eylea Pre-filled Syringe may cause serious side effects. Call your doctor at once if you have:

• eye pain or redness, swelling around your eyes;

• sudden vision problems;

• seeing flashes of light or "floaters" in your vision, seeing halos around lights;

• your eyes may be more sensitive to light;

• chest pain;

• sudden numbness or weakness, especially on one side of the body; or

• sudden severe headache, confusion, problems with speech or balance.

Common side effects of Eylea Pre-filled Syringe may include:

• red or watery eyes;

• broken blood vessels in the eye;

• blurred vision;

• swelling of the eyelids; or

• mild eye pain or discomfort after the injection.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects. You may report side effects to FDA at 1-800-FDA-1088.

Warnings

You should not use aflibercept if you have swelling inside your eyes, or any type of infection in or around your eyes.

Call your doctor at once if you have eye pain or redness, swelling or puffiness around your eyes, or sudden vision problems at any time during treatment.

Before taking this medicine

You should not use aflibercept if you are allergic to it, or if you have:

• swelling inside your eyes; or

• any type of infection (bacterial, fungal, viral) in or around your eyes.

Tell your doctor if you have ever had:

• inflammation of the eye or retina, retinal detachment;

• a blood clot or stroke; or

• glaucoma or another condition that increases pressure inside your eyes.

Tell your doctor if you are pregnant or plan to become pregnant. Use effective birth control to prevent pregnancy before your first dose of Eylea Pre-filled Syringe. Keep using birth control during treatment and for at least 3 months after your last injection.

Do not breastfeed.

How is Eylea Pre-filled Syringe given?

Eylea Pre-filled Syringe is given as an injection into your eye. Your doctor will use a medicine to numb your eye before giving you the injection. You will receive this injection in your doctor's office or other clinic setting.

For some time after your injection, your eyes will be checked periodically to make sure the injection has not caused any side effects.

Aflibercept is given at different intervals, depending on the condition being treated with this medicine. Follow your doctor's dosing instructions very carefully.

What happens if I miss a dose?

Call your doctor for instructions if you miss an appointment for your aflibercept injection.

What happens if I overdose?

Seek emergency medical attention or call the Poison Help line at 1-800-222-1222.

What should I avoid while using Eylea Pre-filled Syringe?

Eylea Pre-filled Syringe may cause blurred vision and may impair your reactions. Avoid driving or hazardous activity until you know how this medicine will affect you.

What other drugs will affect Eylea Pre-filled Syringe?

Medicine used in the eyes is not likely to be affected by other drugs you use. But many drugs can interact with each other. Tell each of your healthcare providers about all medicines you use, including prescription and over-the-counter medicines, vitamins, and herbal products.

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Further information

Remember, keep this and all other medicines out of the reach of children, never share your medicines with others, and use this medication only for the indication prescribed.

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer

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