Eylea Side Effects

Generic name: aflibercept ophthalmic

Note: This document contains side effect information about aflibercept ophthalmic. Some of the dosage forms listed on this page may not apply to the brand name Eylea.

Some side effects of Eylea may not be reported. Always consult your doctor or healthcare specialist for medical advice. You may also report side effects to the FDA.

For the Consumer

Applies to aflibercept ophthalmic: intraocular solution

Get emergency medical help if you have any of these signs of an allergic reaction while taking aflibercept ophthalmic (the active ingredient contained in Eylea) hives; difficult breathing; swelling of your face, lips, tongue, or throat.

Call your doctor at once if you have:

• eye pain or redness, swelling around your eyes;

• sudden vision problems;

• seeing flashes of light or "floaters" in your vision;

• eyes being more sensitive to light;

• sudden numbness or weakness, especially on one side of the body; or

• sudden severe headache, confusion, problems with speech or balance.

Common side effects may include:

• watery eyes;

• blurred vision;

• swelling of the eyelids; or

• mild eye pain or discomfort after the injection.

This is not a complete list of side effects and others may occur. Call your doctor for medical advice about side effects.

For Healthcare Professionals

Applies to aflibercept ophthalmic: intraocular solution

Ocular

Ocular side effects have included endophthalmitis, retinal detachments, conjunctival hemorrhage, eye pain, cataract, vitreous detachment, vitreous floaters, and increased intraocular pressure. Conjunctival hyperemia, corneal erosion, detachment of the retinal pigment epithelium, foreign body sensation in eyes, increased lacrimation, blurred vision, retinal pigment epithelium tear, eyelid edema, corneal edema have also been reported.

Local

Local side effects have included injection site hemorrhage and injection site pain.

Cardiovascular

Cardiovascular side effects of intravitreal use of VEGF inhibitors have included arterial thromboembolic events such as nonfatal stroke, nonfatal myocardial infarction, or vascular death.

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