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calcium glubionate

Generic Name: calcium glubionate (KAL see um glue BYE oh nate)
Brand Name: Calciquid, Neo-Calglucon, Calcionate

What is calcium glubionate?

Calcium is a mineral that is found naturally in foods. Calcium is necessary for many normal functions of the body, especially bone formation and maintenance. Calcium can also bind to other minerals (such as phosphate) and aid in their removal from the body.

Calcium glubionate is used to prevent and to treat calcium deficiencies.

Calcium glubionate may also be used for purposes other than those listed in this medication guide.

What is the most important information I should know about calcium glubionate?

Do not take calcium glubionate or antacids containing calcium without first talking to your doctor if you take other medications. Aluminum can decrease the effects of many other medicines by binding to them or by changing the acidity of the stomach or the urine.

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Take calcium with meals to increase its absorption by the body.

Who should not take calcium glubionate?

Before taking this medication, tell your doctor if you

  • have had kidney stones;

  • have parathyroid gland disease;

  • take antacids or other calcium supplements; or

  • take a tetracycline antibiotic such as tetracycline (Sumycin, Achromycin V, and others), demeclocycline (Declomycin), doxycycline (Vibramycin, Monodox, Doxy, and others), minocycline (Minocin, Dynacin, and others), or oxytetracycline (Terramycin, and others).

You may not be able to take calcium glubionate, or you may require a dosage adjustment or special monitoring during treatment if you have any of the conditions, or take any of the medications, listed above.

Talk to your doctor before taking calcium glubionate if you are pregnant. In general, calcium is important for the development of an unborn baby.

Talk to your doctor before taking calcium glubionate if you are breast-feeding. Calcium is important for the development of a breast-feeding baby.

How should I take calcium glubionate?

Take calcium glubionate exactly as directed by your doctor or follow the directions on the package. If you do not understand these directions, ask your pharmacist, nurse, or doctor to explain them to you.

To ensure that you get the correct dose of medicine, measure the liquid form of calcium glubionate with a dose-measuring spoon or cup, not with a regular table spoon. If you do not have a dose-measuring device, ask your pharmacist where you can get one. Since calcium glubionate is available as a syrup, it does not need to be shaken before measuring a dose.

Take calcium with meals to increase its absorption by the body, unless otherwise directed by your doctor.

Store calcium glubionate at room temperature away from moisture and heat.

What happens if I miss a dose?

Take the missed dose as soon as you remember. However, if it is almost time for the next dose, skip the missed dose and take only the next regularly scheduled dose. Do not take a double dose of this medicine unless your doctor directs otherwise.

What happens if I overdose?

Seek emergency medical attention.

Symptoms of a calcium overdose include nausea, vomiting, decreased appetite, constipation, confusion, delirium, stupor, and coma.

What should I avoid while taking calcium glubionate?

If you take other medicines, do not take calcium glubionate without first talking to your doctor.

Calcium glubionate side effects

Stop taking calcium glubionate and seek emergency medical attention if you experience a rare allergic reaction (difficulty breathing; closing of your throat; swelling of your lips, tongue, or face; or hives).

Other, less serious side effects may be more likely to occur. Continue to take calcium glubionate and notify your doctor if you experience

  • nausea or vomiting;

  • decreased appetite;

  • constipation;

  • dry mouth or increased thirst; or

  • increased urination.

Side effects other than those listed here may also occur. Talk to your doctor about any side effect that seems unusual or that is especially bothersome.

See also: Side effects (in more detail)

Calcium glubionate dosing information

Usual Adult Dose for Hypocalcemia:

15 mL orally 3 times a day before meals. Each 5 mL provides 115 mg of elemental calcium. Treatment may also consist of vitamin D orally.

Usual Adult Dose for Hypoparathyroidism:

5 to 15 mL orally 3 times a day before meals. Treatment of this disease may also consist of vitamin D.

Usual Adult Dose for Pseudohypoparathyroidism:

5 to 15 mL orally once a day before the morning meal. Treatment of this disease may also consist of vitamin D.

Usual Adult Dose for Osteoporosis:

15 mL orally 1 to 3 times a day before meals. Osteoporosis can be affected by increased serum parathyroid hormone, excessive alcohol intake, tobacco use, certain drugs (corticosteroids, anticonvulsants, heparin, thyroid hormone), dietary vitamin D, and weight bearing exercise.

Usual Adult Dose for Osteomalacia:

5 to 10 mL orally 3 times a day before meals. Treatment may also include vitamin D.

Usual Pediatric Dose for Hypocalcemia:

Neonatal:
Oral:
Adequate intake (AI): 200 mg/day of elemental calcium. Requirements may vary on prematurity, postnatal age, and other clinical factors. Serum calcium concentrations should be monitored closely to determine the specific needs of the patient.
Hypocalcemia (dose depends on clinical condition and serum calcium level):
Dose expressed in mg of elemental calcium: 50 to 150 mg/kg/day in 4 to 6 divided doses
Maximum dose: 1 g/day
Dose expressed in mg of calcium glubionate: 1200 mg/kg/day in 4 to 6 divided doses

Dosing:
Usual Oral:
Adequate intake (AI): Dosage expressed in terms of elemental calcium:
1 to 6 months: 200 mg/day
7 to 12 months: 260 mg/day

Recommended daily allowance (RDA): Dosage expressed in terms of elemental calcium (during pregnancy and lactation, requirements may change):
1 to 3 years: 700 mg/day
4 to 8 years: 1000 mg/day
9 to 18 years: 1300 mg/day

Dietary supplement:
Dosage based on product containing: 1.8 g calcium glubionate/5 mL (115 mg elemental calcium/5 mL):
Infants less than 12 months: 1 teaspoonful 5 times a day. May mix with juice or formula.
Children less than 4 years: 2 teaspoonfuls 3 times a day
Children 4 years and older and Adolescents: 1 tablespoonful 3 times a day

Hypocalcemia (dose depends on clinical condition and serum calcium level):
Dose expressed in mg of elemental calcium:
Children: 45 to 65 mg/kg/day in 4 divided doses

Dose expressed in mg of calcium glubionate:
Infants and Children: 600 to 2000 mg/kg/day in 4 divided doses up to a maximum of 9 g/day

Daily maintenance calcium: IV:
Infants and Children less than 25 kg: 1 to 2 mEq/kg/day
Children 25 to 45 kg: 0.5 to 1.5 mEq/kg/day
Children greater than 45 kg and Adults: 0.2 to 0.3 mEq/kg/day or 10 to 20 mEq/day

What other drugs will affect calcium glubionate?

Before taking calcium glubionate, tell your doctor if you are taking

  • digoxin (Lanoxin, Lanoxicaps);

  • antacids containing calcium or aluminum;

  • other calcium supplements;

  • calcitriol (Rocaltrol) or vitamin D supplements; or

  • a tetracycline antibiotic such as tetracycline (Sumycin, Achromycin V, and others), demeclocycline (Declomycin), doxycycline (Vibramycin, Monodox, Doxy, and others), minocycline (Minocin, Dynacin, and others), or oxytetracycline (Terramycin, and others).

You may not be able to take calcium glubionate, or you may require a dosage adjustment or special monitoring during your treatment if you are taking any of the medicines listed above.

Drugs other than those listed here may also interact with calcium glubionate. Talk to your doctor and pharmacist before taking any other prescription or over-the-counter medicines or herbal/health supplements.

Where can I get more information?

  • Your doctor, pharmacist, or health care provider may have more information about calcium glubionate.
  • Consultation with a licensed health care professional is advisable before using any herbal/health supplement. Additionally, consultation with a practitioner trained in the uses of herbal/health supplements may be beneficial and coordination of treatment among all health care providers involved may be advantageous. Remember, keep this and all other prescription drug products, over-the-counter drug products, and herbal/health supplements out of the reach of children.
  • Disclaimer: Every effort has been made to ensure that the information provided by Cerner Multum, Inc. ('Multum') is accurate, up-to-date, and complete, but no guarantee is made to that effect. Drug information contained herein may be time sensitive. Multum information has been compiled for use by healthcare practitioners and consumers in the United States and therefore Multum does not warrant that uses outside of the United States are appropriate, unless specifically indicated otherwise. Multum's drug information does not endorse drugs, diagnose patients or recommend therapy. Multum's drug information is an informational resource designed to assist licensed healthcare practitioners in caring for their patients and/or to serve consumers viewing this service as a supplement to, and not a substitute for, the expertise, skill, knowledge and judgment of healthcare practitioners. The absence of a warning for a given drug or drug combination in no way should be construed to indicate that the drug or drug combination is safe, effective or appropriate for any given patient. Multum does not assume any responsibility for any aspect of healthcare administered with the aid of information Multum provides. The information contained herein is not intended to cover all possible uses, directions, precautions, warnings, drug interactions, allergic reactions, or adverse effects. If you have questions about the drugs you are taking, check with your doctor, nurse or pharmacist.

Copyright 1996-2012 Cerner Multum, Inc. Version: 2.03. Revision Date: 2/13/04 4:05:23 PM.

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