How does Zinbryta work?
Zinbryta (daclizumab) is an interleukin-2 receptor blocking antibody for the treatment of adults with relapsing forms of multiple sclerosis (MS). It is thought to work by decreasing T-cells and pro-inflammatory lymphoid tissue inducer cells, and increasing CD56bright natural killer (NK) cells, important cells that help regulate the immune system.
Zinbryta should only be used in patients who have had an inadequate response to two or more multiple sclerosis drugs.
The Zinbryta product label carries a boxed warning advising the serious safety risks, including liver injury and immune disorders.
Zinbryta is available only through a restricted distribution program under a Risk Evaluation and Mitigation Strategy.
In March 2018, Biogen and AbbVie announced the voluntary worldwide withdrawal of Zinbryta.
Read next
Related medical questions
- What are the new drugs used for multiple sclerosis (MS)?
- What are the early warning signs of Multiple Sclerosis?
- How do you test for multiple sclerosis?
- Prednisone vs Prednisolone - What's the difference?
- Is Kesimpta better than Ocrevus?
- What are 8 key Kesimpta side effects to watch out for?
- How much does an Ocrevus infusion cost?
- Who is the actress in the Kesimpta commercial?
- Is Tecfidera an immunosuppressant?
- How do Vumerity and Tecfidera compare for multiple sclerosis (MS)?
- How long does it take Ocrevus to work?
- Can I stop taking Tecfidera? What happens if I do?
- Is Ocrevus a form of chemotherapy?
- How long does an Ocrevus infusion take?
- What causes flushing with Tecfidera?
- Can you drink alcohol while taking Tecfidera?
- Where and how should Copaxone be injected?
- Does Tysabri suppress the immune system?
- How does Ocrevus work for MS?
- How effective is Mavenclad for MS?
- Ocrevus vs Aubagio: How do they compare for MS?
- How long can you take Tysabri for?
- Gilenya vs Tecfidera. How do they compare?
- How long can you take Tecfidera?
- What happens when you stop taking Gilenya?
- How quickly does Mavenclad work?
- Does Aubagio suppress the immune system?
- Is Mavenclad a chemotherapy drug?
- Can Gilenya cause weight gain?
- Can Tecfidera cause stomach damage?
Drug information
- Zinbryta Information for Consumers
- Zinbryta prescribing info & package insert (for Health Professionals)
- Side Effects of Zinbryta (detailed)
Related support groups
- Zinbryta (2 questions, 3 members)
- Multiple Sclerosis (90 questions, 549 members)