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Can Fycompa cause hair loss?

Medically reviewed by Carmen Pope, BPharm. Last updated on Oct 11, 2022.

Official answer

by Drugs.com

Hair loss is not a reported side effect of Fycompa, and there were few anecdotal reports of hair loss associated with the drug on blog sites. There was one report of a 13-year-old girl who developed hair curling after a few weeks of Fycompa treatment for uncontrolled seizures associated with Pitt-Hopkins syndrome.

References
  • Calle-Lopez, Y., Kotagal, P., & Knight, E. P. (2019). Perampanel-induced hair curling in a patient with epilepsy associated with Pitt Hopkins syndrome. Epileptic disorders : international epilepsy journal with videotape, 21(5), 479–482. https://doi.org/10.1684/epd.2019.1103

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Weight gain is a common dose-related side effect of Fycompa (perampanel), a non-competitive AMPA glutamate receptor antagonist used to treat epilepsy. It occurs in about 4 percent of patients treated with an 8 mg or 12 mg dose of the drug. Monitoring for weight gain is recommended while being treated with Fycompa. Continue reading

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