Drug Interaction Report
6 potential interactions and/or warnings found for the following 2 drugs:
- atazanavir
- Tri-Sprintec (ethinyl estradiol / norgestimate)
Interactions between your drugs
ethinyl estradiol atazanavir
Applies to: Tri-Sprintec (ethinyl estradiol / norgestimate), atazanavir
Ask your doctor before using ethinyl estradiol together with atazanavir. Atazanavir may affect the safety and decrease the birth control effectiveness of ethinyl estradiol. Women who use birth control pills or birth control patches should choose a different kind of contraception during atazanavir therapy. Using ethinyl estradiol together with atazanavir can also increase the blood levels or add to the side effects of ethinyl estradiol. This can cause sudden headache, confusion, pain behind the eyes, problems with vision, speech, or balance, nausea, and stomach pain. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
norgestimate atazanavir
Applies to: Tri-Sprintec (ethinyl estradiol / norgestimate), atazanavir
Ask your doctor before using norgestimate together with atazanavir. Atazanavir may affect the safety and decrease the birth control effectiveness of norgestimate. Women who use birth control pills or birth control patches should choose a different kind of contraception during atazanavir therapy. Using norgestimate together with atazanavir can also increase the blood levels or add to the side effects of norgestimate. This can cause sudden headache, confusion, pain behind the eyes, problems with vision, speech, or balance, nausea, and stomach pain. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
norgestimate food
Applies to: Tri-Sprintec (ethinyl estradiol / norgestimate)
Grapefruit juice may increase the blood levels of certain medications such as norgestimate. You may want to limit your consumption of grapefruit and grapefruit juice during treatment with norgestimate. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Contact your doctor if your condition changes or you experience increased side effects. Orange juice is not expected to interact.
atazanavir food
Applies to: atazanavir
Food can enhance the levels of atazanavir in your body. To ensure maximal oral absorption, atazanavir should be administered with or immediately after a meal. This will make it easier for your body to absorb the medication.
ethinyl estradiol food
Applies to: Tri-Sprintec (ethinyl estradiol / norgestimate)
Information for this minor interaction is available on the professional version.
ethinyl estradiol food
Applies to: Tri-Sprintec (ethinyl estradiol / norgestimate)
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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