Drug Interaction Report
18 potential interactions and/or warnings found for the following 12 drugs:
- allopurinol
- Ativan (lorazepam)
- Colcrys (colchicine)
- gabapentin
- green tea
- hydralazine
- Lasix (furosemide)
- milk thistle
- nabumetone
- pantoprazole
- Synthroid (levothyroxine)
- turmeric
Interactions between your drugs
furosemide LORazepam
Applies to: Lasix (furosemide), Ativan (lorazepam)
Furosemide and LORazepam may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
hydrALAZINE LORazepam
Applies to: hydralazine, Ativan (lorazepam)
HydrALAZINE and LORazepam may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
hydrALAZINE colchicine
Applies to: hydralazine, Colcrys (colchicine)
Using hydrALAZINE together with colchicine may increase the risk of nerve damage, which is a potential side effect of both medications. Talk to your doctor if you have any questions or concerns. Your doctor may be able to prescribe alternatives that do not interact, or you may need a dose adjustment or more frequent monitoring to safely use both medications. Let your doctor know if you develop weakness, numbness, pain, burning, or tingling in your hands, feet, or limbs. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
furosemide nabumetone
Applies to: Lasix (furosemide), nabumetone
Before taking furosemide, tell your doctor if you also use nabumetone. You may need dose adjustments or special tests in order to safely take both medications together. If you are receiving this combination drink plenty of water. Blood pressure and kidney function should be monitored as well. It is important that you tell your healthcare provider about all other medications that you are using including vitamins and herbs. Do not stop using your medications without first talking to your doctor.
hydrALAZINE nabumetone
Applies to: hydralazine, nabumetone
Before taking hydrALAZINE, tell your doctor if you also use nabumetone. This combination may cause dizziness, headaches, or blurred vision. If you take both medications together, tell your doctor if you have any of these symptoms. You may need a dose adjustment or need your blood pressure checked more often. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
LORazepam gabapentin
Applies to: Ativan (lorazepam), gabapentin
Using LORazepam together with gabapentin may increase side effects such as dizziness, drowsiness, confusion, and difficulty concentrating. Some people, especially the elderly, may also experience impairment in thinking, judgment, and motor coordination. You should avoid or limit the use of alcohol while being treated with these medications. Also avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medications affect you. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
furosemide pantoprazole
Applies to: Lasix (furosemide), pantoprazole
Chronic use of drugs known as proton pump inhibitors including pantoprazole can sometimes cause hypomagnesemia (low blood levels of magnesium), and the risk may be further increased when combined with other medications that also have this effect such as furosemide. In severe cases, hypomagnesemia can lead to irregular heart rhythm, palpitations, muscle spasm, tremor, and seizures. In children, abnormal heart rhythm may cause fatigue, upset stomach, dizziness, and lightheadedness. A dose adjustment or more frequent monitoring by the doctor may be required to safely use both medications. If you are using an over-the-counter proton pump inhibitor medication such as Prilosec OTC, Zegerid OTC or Prevacid 24 HR, you should follow the directions on the package carefully. Do not use the medication more frequently or for a longer period than recommended on the label unless otherwise prescribed by your doctor. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
levothyroxine pantoprazole
Applies to: Synthroid (levothyroxine), pantoprazole
Taking levothyroxine with pantoprazole may interfere with the absorption of levothyroxine and reduce its effectiveness. Contact your doctor if you experience signs and symptoms of reduced thyroid function such as fatigue; sluggishness; constipation; depression; hoarseness; unexplained weight gain; sensitivity to cold; pale, dry skin; muscle aches, weakness, or tenderness; joint pain, stiffness, or swelling; heavier than normal menstruation periods; or brittle fingernails and hair. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor
nabumetone turmeric
Applies to: nabumetone, turmeric
Talk to your doctor before using turmeric together with nabumetone. There is some concern that products containing turmeric or curcumin (an active component of turmeric) may affect platelet function and clotting, increasing the risk of bleeding when combined with medications that have blood thinning effects such as nabumetone. You may need more frequent monitoring by your doctor to safely use both medications. You should seek immediate medical attention if you experience any unusual bleeding or bruising, or have other signs and symptoms of bleeding such as dizziness; lightheadedness; red or black, tarry stools; coughing up or vomiting fresh or dried blood that looks like coffee grounds; severe headache; and weakness. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
furosemide hydrALAZINE
Applies to: Lasix (furosemide), hydralazine
Information for this minor interaction is available on the professional version.
No other interactions were found between your selected drugs. However, this does not necessarily mean no other interactions exist. Always consult your healthcare provider.
Drug and food interactions
colchicine food
Applies to: Colcrys (colchicine)
Drinking large amounts of grapefruit juice can increase your blood levels of colchicine to dangerous levels. You should avoid the consumption of grapefruit or grapefruit juice during treatment with colchicine. Let your doctor know if you experience abdominal pain, nausea, vomiting, diarrhea, fever, muscle pain, weakness, fatigue, and/or numbness or tingling in your hands and feet, as these may be early symptoms of colchicine toxicity.
LORazepam food
Applies to: Ativan (lorazepam)
Alcohol can increase the nervous system side effects of LORazepam such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with LORazepam. Do not use more than the recommended dose of LORazepam, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.
levothyroxine food
Applies to: Synthroid (levothyroxine)
The timing of meals relative to your oral levothyroxine dose can affect the absorption of the medication. Therefore, levothyroxine should be taken on a consistent schedule with regard to time of day and relation to meals to avoid large fluctuations in blood levels, which may alter its effects. In addition, absorption of levothyroxine may be decreased and/or delayed by foods such as soybean flour, cotton seed meal, walnuts, dietary fiber, calcium, calcium fortified juices and grapefruit or grapefruit juice. These foods should be avoided within several hours of dosing if possible. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
gabapentin food
Applies to: gabapentin
Alcohol can increase the nervous system side effects of gabapentin such as dizziness, drowsiness, and difficulty concentrating. Some people may also experience impairment in thinking and judgment. You should avoid or limit the use of alcohol while being treated with gabapentin. Do not use more than the recommended dose of gabapentin, and avoid activities requiring mental alertness such as driving or operating hazardous machinery until you know how the medication affects you. Talk to your doctor or pharmacist if you have any questions or concerns.
furosemide food
Applies to: Lasix (furosemide)
Furosemide and ethanol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
hydrALAZINE food
Applies to: hydralazine
HydrALAZINE and ethanol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
nabumetone food
Applies to: nabumetone
Ask your doctor before using nabumetone together with ethanol. Do not drink alcohol while taking nabumetone. Alcohol can increase your risk of stomach bleeding caused by nabumetone. Call your doctor at once if you have symptoms of bleeding in your stomach or intestines. This includes black, bloody, or tarry stools, or coughing up blood or vomit that looks like coffee grounds. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
levothyroxine food
Applies to: Synthroid (levothyroxine)
Using multivitamin with minerals together with levothyroxine may decrease the effects of levothyroxine. You should separate the administration of levothyroxine and multivitamin with minerals by at least 4 hours. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
No duplication warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
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Further information
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