Promethazine VC Plain and Alcohol/Food Interactions
There are 2 alcohol/food/lifestyle interactions with Promethazine VC Plain (phenylephrine / promethazine).
Phenylephrine Caffeine
Moderate Drug Interaction
Both phenylephrine and caffeine can increase blood pressure and heart rate, and combining them may enhance these effects. Talk to your doctor before using these medications, especially if you have a history of high blood pressure or heart disease. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. Contact your doctor if your condition changes or you experience increased side effects. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Promethazine Alcohol (Ethanol)
Moderate Drug Interaction
Ask your doctor before using promethazine together with ethanol. This can cause uncontrollable movements, agitation, seizures, severe dizziness or fainting, coma, very deep sleep, irregular heartbeats, and high or low body temperature. Use caution when driving, operating machinery, or performing other hazardous activities, these medicaions may cause dizziness or drowsiness. If you experience dizziness or drowsiness, avoid these activities. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Promethazine VC Plain drug interactions
There are 735 drug interactions with Promethazine VC Plain (phenylephrine / promethazine).
Promethazine VC Plain disease interactions
There are 22 disease interactions with Promethazine VC Plain (phenylephrine / promethazine) which include:
- acute alcohol intoxication
- cardiovascular disease
- CNS depression
- head injury
- antidopaminergic effects 1
- asthma
- cardiovascular disease
- anticholinergic effects
- asthma/COPD
- breast cancer
- dystonic reactions
- hematologic toxicity
- liver disease
- NMS
- parkinsonism
- renal dysfunction
- seizure disorders
- tardive dyskinesia
- antidopaminergic effects 2
- BPH
- diabetes
- glaucoma
More about Promethazine VC Plain (phenylephrine / promethazine)
- Promethazine VC Plain consumer information
- Check interactions
- Compare alternatives
- Side effects
- Dosage information
- During pregnancy
- Drug class: upper respiratory combinations
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.