Estring (estradiol topical) Alcohol, Food & Lifestyle Interactions

There are 2 food and lifestyle interactions with Estring (estradiol topical) which include:

estrogens - hypertension

The risk of myocardial infarction and strokes, including those associated with oral contraceptive use and some estrogen use, is increased in patients with hypertension. Moreover, estrogens (and also progestogens) may elevate blood pressure and worsen the hypertension, thus compounding the risk. Clinically significant blood pressure increases have been reported during estrogen therapy, particularly in patients receiving high dosages or treated with oral contraceptive combinations having high progestational activity. These effects also increase with duration of therapy and patient age. Therapy with estrogens should be administered cautiously in patients with preexisting hypertension. Patients should be monitored for changes in cardiovascular status, and their antihypertensive regimen adjusted or estrogen therapy withdrawn as necessary. In patients requiring contraception, alternative methods should be considered for those who are hypertensive, over age 35, and smoke.

estrogens - hyperlipidemia

Although estrogens have generally favorable effects on plasma lipids, including increases in HDL and decreases in total cholesterol and LDL, they have also been associated with significant elevations in triglyceride levels, particularly when high dosages are used. Severe hyperlipidemia is known to sometimes cause pancreatitis. Patients with preexisting hyperlipidemia may require closer monitoring during estrogen therapy, and adjustments made accordingly in their lipid-lowering regimen.

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Estring (estradiol topical) drug Interactions

There are 161 drug interactions with Estring (estradiol topical)

Estring (estradiol topical) disease Interactions

There are 14 disease interactions with Estring (estradiol topical) which include:

Abnormal Vaginal Bleeding Carcinomas (Estrogenic) Hypercalcemia In Breast Cancer Hypertension Thromboembolism/Cardiovascular Hepatic Neoplasms Gallbladder Disease

Hypercalcemia Hyperlipidemia Liver Disease Depression Fluid Retention Glucose Intolerance Thyroid Function Tests

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