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Diacetazone and Alcohol/Food Interactions

There are 2 alcohol/food/lifestyle interactions with Diacetazone (acetaminophen / dichloralphenazone / isometheptene mucate).

Moderate

dichloralphenazone food

Moderate Food Interaction

Consumer information for this interaction is not currently available.

GENERALLY AVOID: Alcohol may potentiate some of the pharmacologic effects of CNS-active agents. Use in combination may result in additive central nervous system depression and/or impairment of judgment, thinking, and psychomotor skills.

MANAGEMENT: Patients receiving CNS-active agents should be warned of this interaction and advised to avoid or limit consumption of alcohol. Ambulatory patients should be counseled to avoid hazardous activities requiring complete mental alertness and motor coordination until they know how these agents affect them, and to notify their physician if they experience excessive or prolonged CNS effects that interfere with their normal activities.

References

  1. Warrington SJ, Ankier SI, Turner P "Evaluation of possible interactions between ethanol and trazodone or amitriptyline." Neuropsychobiology 15 (1986): 31-7
  2. Gilman AG, eds., Nies AS, Rall TW, Taylor P "Goodman and Gilman's the Pharmacological Basis of Therapeutics." New York, NY: Pergamon Press Inc. (1990):
  3. "Product Information. Fycompa (perampanel)." Eisai Inc (2012):
  4. "Product Information. Rexulti (brexpiprazole)." Otsuka American Pharmaceuticals Inc (2015):
View all 4 references
Major

High Blood Pressure (Hypertension)

Major Potential Hazard, Moderate plausibility

isometheptene mucate - vascular effects

The use of combination drugs that have isometheptene mucate may be contraindicated in patients with glaucoma and/or severe cases of renal disease, hypertension, organic heart disease, or hepatic disease.

References

  1. "Product Information. Midrin (APAP/dichloralphenazone/isometheptene)." Carnrick Laboratories Inc (2022):
  2. "Product Information. Prodrin (acetaminophen/caffeine/isometheptene mucate)." WraSer Pharmaceuticals (2022):

Diacetazone drug interactions

There are 421 drug interactions with Diacetazone (acetaminophen / dichloralphenazone / isometheptene mucate).

Diacetazone disease interactions

There are 7 disease interactions with Diacetazone (acetaminophen / dichloralphenazone / isometheptene mucate) which include:

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More about Diacetazone (acetaminophen / dichloralphenazone / isometheptene mucate)

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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