Drug Interactions between Tecfidera and Vumerity
This report displays the potential drug interactions for the following 2 drugs:
- Tecfidera (dimethyl fumarate)
- Vumerity (diroximel fumarate)
Interactions between your drugs
dimethyl fumarate diroximel fumarate
Applies to: Tecfidera (dimethyl fumarate) and Vumerity (diroximel fumarate)
Using dimethyl fumarate together with diroximel fumarate is not recommended. These medications are very similar and may have additive effects when combined. This may increase the risk and/or severity of side effects such as low white blood cell count, serious and potentially life-threatening infections, liver problems, flushing, redness, itching, and rash. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Drug and food interactions
diroximel fumarate food
Applies to: Vumerity (diroximel fumarate)
Taking diroximel fumarate with high-fat, high-calorie meals or snacks may reduce the levels of active medication in the blood, which may make the medication less effective in treating your condition. Food may help improve the tolerability of diroximel fumarate if you are experiencing flushing or gastrointestinal side effects from the medication; however, meals or snacks should contain no more than 700 calories and no more than 30 grams of fat. In addition, you should avoid or limit the use of alcohol while being treated with diroximel fumarate. Talk to your doctor or pharmacist if you have questions on how to take this or other medications you are prescribed. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
dimethyl fumarate food
Applies to: Tecfidera (dimethyl fumarate)
Information for this minor interaction is available on the professional version.
Therapeutic duplication warnings
Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.
Fumaric acid
Therapeutic duplication
The recommended maximum number of medicines in the 'fumaric acid' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'fumaric acid' category:
- Tecfidera (dimethyl fumarate)
- Vumerity (diroximel fumarate)
Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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