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Drug Interactions between COVID-19 mRNA (Moderna) vaccine and smallpox vaccine

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

smallpox vaccine SARS-CoV-2 (COVID-19) mRNA-LNP vaccine (cvx 311)

Applies to: smallpox vaccine and COVID-19 mRNA (Moderna) vaccine

Vaccination with smallpox vaccine and SARS-CoV-2 (COVID-19) mRNA-LNP vaccine (cvx 311) at the same time or within a short time of each other may increase the risk of myopericarditis, or inflammation of the heart muscle and lining of the heart. These vaccines individually may be associated with a rare risk of developing myopericarditis, but the risk may be greater when they are administered together, particularly in adolescent or young adult males. If feasible, it may be advisable to wait 4 weeks in between the two vaccines, unless there is an outbreak that requires prompt vaccination. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

Medical Disclaimer