Drug Interactions between glycopyrrolate / neostigmine and rivastigmine
This report displays the potential drug interactions for the following 2 drugs:
- glycopyrrolate/neostigmine
- rivastigmine
Interactions between your drugs
neostigmine glycopyrrolate
Applies to: glycopyrrolate / neostigmine and glycopyrrolate / neostigmine
Ask your doctor before using neostigmine together with glycopyrrolate. Using these medications together can cause increasing muscle weakness. In addition, such use may mask the less serious, gastrointestinal signs of glycopyrrolate overdose and lead to difficulty breathing, chest pain, and possibly death. If your doctor prescribes these medications together, you may need a dose adjustment or special tests to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
neostigmine rivastigmine
Applies to: glycopyrrolate / neostigmine and rivastigmine
Using neostigmine together with rivastigmine can increase the blood levels or add to the side effects of either medication. This can cause nausea, vomiting, diarrhea, abdominal pain, increased salivation, cold sweats, slow or irregular heartbeat, muscle weakness or cramps, dizziness, headache, seizures, or breathing problems. If your doctor does prescribe these medications together, you may need a dose adjustment or special test to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
glycopyrrolate rivastigmine
Applies to: glycopyrrolate / neostigmine and rivastigmine
Using rivastigmine together with glycopyrrolate may decrease the benefits of rivastigmine in the treatment of dementia. Rivastigmine may also counteract the benefit of glycopyrrolate. Glycopyrrolate should generally be avoided in patients with Alzheimer's disease or other cognitive problems. Glycopyrrolate may also adversely affect elderly patients by producing symptoms ranging from mild thinking impairment to delirium. It is important that you tell your healthcare provider about all other medications that you are using including vitamins and herbs. Do not stop using your medications without first talking to your doctor.
Drug and food interactions
glycopyrrolate food
Applies to: glycopyrrolate / neostigmine
Ask your doctor before using glycopyrrolate together with ethanol. Use alcohol cautiously. Alcohol may increase drowsiness and dizziness while you are taking glycopyrrolate. You should be warned not to exceed recommended dosages and to avoid activities requiring mental alertness. If your doctor prescribes these medications together, you may need a dose adjustment to safely take this combination. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.
Therapeutic duplication warnings
Therapeutic duplication is the use of more than one medicine from the same drug category or therapeutic class to treat the same condition. This can be intentional in cases where drugs with similar actions are used together for demonstrated therapeutic benefit. It can also be unintentional in cases where a patient has been treated by more than one doctor, or had prescriptions filled at more than one pharmacy, and can have potentially adverse consequences.
Cholinergics
Therapeutic duplication
The recommended maximum number of medicines in the 'cholinergics' category to be taken concurrently is usually one. Your list includes two medicines belonging to the 'cholinergics' category:
- glycopyrrolate/neostigmine
- rivastigmine
Note: In certain circumstances, the benefits of taking this combination of drugs may outweigh any risks. Always consult your healthcare provider before making changes to your medications or dosage.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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