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Drug Interactions between glyburide and methoxsalen

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

glyBURIDE methoxsalen

Applies to: glyburide and methoxsalen

Methoxsalen sensitizes your skin to sunlight, and combining it with other medications that can also have this effect (i.E., photosensitivity) such as glyBURIDE may increase the risk of a severe sunburn. Check with your doctor to see if you should temporarily withhold any of your medications before and after treatment with methoxsalen. Following treatment, you should avoid exposure of the eyes and skin to sunlight or artificial UV rays (e.G., sunlamps or tanning beds ) for at least 24 hours. If sun exposure is unavoidable, you should use suitable covering (e.G., hat and gloves, long-sleeved clothing) or a topical sunscreen (SPF 15 or higher), along with wrap-around UVA- absorbing sunglasses to prevent cataracts, for the 24 hour period following treatment, whether exposed to direct or indirect sunlight in the open or through a window glass. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

glyBURIDE food

Applies to: glyburide

Alcohol may affect blood glucose levels in patients with diabetes. Both hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar) may occur, depending on how much and how often you drink. You should avoid using alcohol if your diabetes is not well controlled or if you have high triglycerides, neuropathy (nerve damage), or pancreatitis. Moderate alcohol consumption generally does not affect blood glucose levels if your diabetes is under control. However, it may be best to limit alcohol intake to one drink daily for women and two drinks daily for men (1 drink = 5 oz wine, 12 oz beer, or 1.5 oz distilled spirits) in conjunction with your normal meal plan. Avoid drinking alcohol on an empty stomach or following exercise, as it may increase the risk of hypoglycemia. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

methoxsalen food

Applies to: methoxsalen

Methoxsalen should be administered with food or milk. This may make it easier for your body to tolerate the medication. Avoid eating or coming in contact with limes, figs, parsley, parsnips, rue (Ruta graveolens), mustard, carrots and celery. This can increase the risk of photosensitivity and cause your skin to burn more easily. Avoid prolonged exposure to sunlight, sunlamps, or tanning beds. Methoxsalen make your skin more sensitive to sunlight, and a sunburn may result. Wear protective clothing and use a sunscreen if you must be in the sun. Call your doctor if you have severe burning, redness, itching, rash, or swelling after being in the sun.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.