Drug interactions between Gesticare DHA and NegGram
| Results for the following 2 drugs: |
|---|
| Gesticare DHA (multivitamin, prenatal) |
| NegGram (nalidixic acid) |
Interactions between your selected drugs
nalidixic acid ↔ multivitamin, prenatal
Applies to:NegGram (nalidixic acid) and Gesticare DHA (multivitamin, prenatal)
ADJUST DOSING INTERVAL: Oral preparations that contain magnesium, aluminum, or calcium may significantly decrease the absorption of nalidixic acid. Absorption may also be reduced by sucralfate, which contains aluminum, as well as other polyvalent cations such as iron and zinc. The mechanism is chelation of nalidixic acid by these cations, forming a complex that is poorly absorbed from the gastrointestinal tract.
MANAGEMENT: When coadministration cannot be avoided, nalidixic acid should be dosed at least 2 hours before or 2 hours after any polyvalent cation-containing product to minimize the potential for interaction.
See also...
Drug Interaction Classification
The classifications below are a guideline only. The relevance of a particular drug interaction to a specific patient is difficult to determine using this tool alone given the large number of variables that may apply.
| Major | Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. |
| Moderate | Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. |
| Minor | Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. |
Do not stop taking any medications without consulting your healthcare provider.
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