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Drug Interactions between fosphenytoin and Versed

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

midazolam fosphenytoin

Applies to: Versed (midazolam) and fosphenytoin

Talk to your doctor before using fosphenytoin together with midazolam. Medications like midazolam can alter the blood levels and effects of fosphenytoin. Contact your doctor if you experience loss of seizure control or symptoms that may suggest excessive fosphenytoin levels such as nausea, vomiting, twitching eye movements, blurred vision, slurred speech, loss of balance or coordination, tremors, sluggishness, confusion, or hallucinations. You may need a dose adjustment or more frequent monitoring by your doctor to safely use both medications. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

midazolam food

Applies to: Versed (midazolam)

Grapefruit and grapefruit juice may interact with midazolam and lead to potentially dangerous side effects. Discuss the use of grapefruit products with your doctor. Do not increase or decrease the amount of grapefruit products in your diet without first talking to your doctor. Do not drink alcohol while taking midazolam. This medication can increase the effects of alcohol. You may feel more drowsy, dizzy, or tired if you take midazolam with alcohol. Talk to your doctor or pharmacist if you have any questions or concerns.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.