Drug Interactions between Flumezide and methylene blue

Before taking bendroflumethiazide, tell your doctor if you also use rauwolfia serpentina. You may need dose adjustments or special tests in order to safely take both medications together. The blood pressure lowering effects of this combination may be additive. You should take rauwolfia serpentina at bedtime and to notify your doctor if have dizziness or feel faint. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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If you are currently being treated or have recently been treated with methylene blue, initiating rauwolfia serpentina may cause high blood pressure and nervous system stimulation. You should generally wait at least 14 days after you are off methylene blue before you start using rauwolfia serpentina. On the other hand, the interaction may not occur if you have been receiving rauwolfia serpentina and are starting treatment with methylene blue. Talk to your doctor if you have any questions or concerns. You should seek immediate medical attention if you experience sudden and severe headache, blurred vision, confusion, seizures, chest pain, nausea or vomiting, sudden numbness or weakness (especially on one side of the body), speech difficulties, fever, sweating, lightheadedness, and/or fainting during treatment with these medications, as these may be signs and symptoms of excessively high blood pressure. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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