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Drug Interactions between Flumezide and insulin lispro protamine

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

bendroflumethiazide rauwolfia serpentina

Applies to: Flumezide (bendroflumethiazide / rauwolfia serpentina) and Flumezide (bendroflumethiazide / rauwolfia serpentina)

Before taking bendroflumethiazide, tell your doctor if you also use rauwolfia serpentina. You may need dose adjustments or special tests in order to safely take both medications together. The blood pressure lowering effects of this combination may be additive. You should take rauwolfia serpentina at bedtime and to notify your doctor if have dizziness or feel faint. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

bendroflumethiazide insulin lispro protamine

Applies to: Flumezide (bendroflumethiazide / rauwolfia serpentina) and insulin lispro protamine

Bendroflumethiazide may interfere with blood glucose control and reduce the effectiveness of insulin lispro protamine and other diabetic medications. Monitor your blood sugar levels closely. You may need a dose adjustment of your diabetic medications during and after treatment with bendroflumethiazide. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

rauwolfia serpentina insulin lispro protamine

Applies to: Flumezide (bendroflumethiazide / rauwolfia serpentina) and insulin lispro protamine

Using rauwolfia serpentina together with insulin or certain other diabetes medications may increase the risk of hypoglycemia, or low blood sugar. In addition, rauwolfia serpentina may mask some of the symptoms of hypoglycemia such as tremor, palpitation and rapid heartbeat, making it more difficult to recognize an oncoming episode. Other symptoms of hypoglycemia such as headache, dizziness, drowsiness, nervousness, confusion, nausea, hunger, weakness, and perspiration are not affected. Talk to your doctor if you have any questions or concerns. You may need to monitor your blood glucose levels more frequently, especially if you are prone to developing hypoglycemia. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Moderate

insulin lispro protamine food

Applies to: insulin lispro protamine

Alcohol may affect blood glucose levels in patients with diabetes. Both hypoglycemia (low blood sugar) and hyperglycemia (high blood sugar) may occur, depending on how much and how often you drink. You should avoid using alcohol if your diabetes is not well controlled or if you have high triglycerides, neuropathy (nerve damage), or pancreatitis. Moderate alcohol consumption generally does not affect blood glucose levels if your diabetes is under control. However, it may be best to limit alcohol intake to one drink daily for women and two drinks daily for men (1 drink = 5 oz wine, 12 oz beer, or 1.5 oz distilled spirits) in conjunction with your normal meal plan. Avoid drinking alcohol on an empty stomach or following exercise, as it may increase the risk of hypoglycemia. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

bendroflumethiazide food

Applies to: Flumezide (bendroflumethiazide / rauwolfia serpentina)

Bendroflumethiazide and ethanol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

rauwolfia serpentina food

Applies to: Flumezide (bendroflumethiazide / rauwolfia serpentina)

Rauwolfia serpentina and ethanol may have additive effects in lowering your blood pressure. You may experience headache, dizziness, lightheadedness, fainting, and/or changes in pulse or heart rate. These side effects are most likely to be seen at the beginning of treatment, following a dose increase, or when treatment is restarted after an interruption. Let your doctor know if you develop these symptoms and they do not go away after a few days or they become troublesome. Avoid driving or operating hazardous machinery until you know how the medications affect you, and use caution when getting up from a sitting or lying position. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.

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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.

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