Drug Interactions between Flomax and Metamucil Smooth Texture
This report displays the potential drug interactions for the following 2 drugs:
- Flomax (tamsulosin)
- Metamucil Smooth Texture (psyllium)
Interactions between your drugs
No interactions were found between Flomax and Metamucil Smooth Texture. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.
Flomax
A total of 293 drugs are known to interact with Flomax.
- Flomax is in the drug class alpha blockers.
- Flomax is used to treat Benign Prostatic Hyperplasia.
Metamucil Smooth Texture
A total of 29 drugs are known to interact with Metamucil Smooth Texture.
- Metamucil smooth texture is in the drug class laxatives.
- Metamucil smooth texture is used to treat the following conditions:
Drug and food interactions
psyllium food
Applies to: Metamucil Smooth Texture (psyllium)
ADJUST DOSING INTERVAL: Bulk-forming laxatives such as guar gum, psyllium, polycarbophil, or methylcellulose may affect the bioavailability of concomitantly administered substances due to their effect on the rate of gastrointestinal transit and gastric emptying.
MANAGEMENT: In general, oral medications should be administered at least 2 hours before or 2 hours after dosing of the bulk-forming laxative.
References
- (2001) "Product Information. Metamucil (psyllium)." Procter and Gamble Pharmaceuticals
tamsulosin food
Applies to: Flomax (tamsulosin)
ADJUST DOSING INTERVAL: Food may delay the gastrointestinal absorption of tamsulosin. The time to maximum plasma concentration (Tmax) is reached by 4 to 5 hours under fasted conditions and by 6 to 7 hours when tamsulosin is administered with food. The delay in Tmax has the desirable effect of smoothing the tamsulosin plasma concentration profile, thereby reducing fluctuation of the plasma peak and trough concentrations with multiple dosing. Food may also affect the extent of absorption of tamsulosin. It has been reported that taking tamsulosin under fasted conditions results in a 30% increase in bioavailability (AUC) and 40% to 70% increase in peak plasma concentration (Cmax) compared to fed conditions. The effects of food on the pharmacokinetics of tamsulosin are consistent regardless of whether tamsulosin is taken with a light meal or a high-fat meal.
MANAGEMENT: To ensure uniformity of absorption, tamsulosin should be administered approximately one-half hour following the same meal each day.
References
- (2001) "Product Information. Flomax (tamsulosin)." Boehringer-Ingelheim
Therapeutic duplication warnings
No warnings were found for your selected drugs.
Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.
See also
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.
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