Subsys Drug Interactions
Currently displaying 258 drugs known to have a major interaction with Subsys (fentanyl).
- 258 major drug interactions
- 351 moderate drug interactions
- 2 minor drug interactions
Major interactions with Subsys (fentanyl)
Note: Showing generic names only.
5
A
- acetylcarbromal
- adagrasib
- almotriptan
- alprazolam
- alvimopan
- aminoglutethimide
- amiodarone
- amitriptyline
- amobarbital
- amoxapine
- amprenavir
- apalutamide
- aprepitant
- aripiprazole
- armodafinil
- asenapine
- atazanavir
B
- baclofen
- belzutifan
- berotralstat
- boceprevir
- bosentan
- brexanolone
- brexpiprazole
- buprenorphine
- bupropion
- buspirone
- butabarbital
- butalbital
- butorphanol
C
- cannabis
- carbamazepine
- cariprazine
- carisoprodol
- cenobamate
- ceritinib
- chloral hydrate
- chloramphenicol
- chlordiazepoxide
- chlormezanone
- chlorphenesin
- chlorpromazine
- chlorzoxazone
- citalopram
- clarithromycin
- clobazam
- clofazimine
- clomipramine
- clonazepam
- clorazepate
- clotrimazole
- clozapine
- cobicistat
- codeine
- conivaptan
- crizotinib
- cyclobenzaprine
D
- dabrafenib
- dantrolene
- daridorexant
- darunavir
- dasatinib
- delavirdine
- desipramine
- desvenlafaxine
- dexamethasone
- dexfenfluramine
- dextromethorphan
- dezocine
- diazepam
- dihydroergotamine
- diltiazem
- dolasetron
- doxepin
- doxepin topical
- dronedarone
- droperidol
- duloxetine
- duvelisib
E
- efavirenz
- elagolix
- eletriptan
- encorafenib
- enzalutamide
- ergotamine
- erythromycin
- escitalopram
- esketamine
- eslicarbazepine
- estazolam
- eszopiclone
- ethchlorvynol
- etravirine
F
- fedratinib
- fenfluramine
- fexinidazole
- fluconazole
- fluoxetine
- fluphenazine
- flurazepam
- fluvoxamine
- fosamprenavir
- fosaprepitant
- fosphenytoin
- frovatriptan
- furazolidone
G
H
I
- idelalisib
- iloperidone
- imatinib
- imipramine
- indinavir
- iohexol
- iomeprol
- iopamidol
- isavuconazonium
- isocarboxazid
- itraconazole
- ivosidenib
K
L
- lasmiditan
- lemborexant
- letermovir
- levoketoconazole
- levomethadyl acetate
- levomilnacipran
- levorphanol
- linezolid
- lonafarnib
- lorazepam
- lorcaserin
- lorlatinib
- loxapine
- lumateperone
- lurasidone
M
- maprotiline
- mavacamten
- meperidine
- mephobarbital
- meprobamate
- mesoridazine
- metaxalone
- methadone
- methocarbamol
- methylene blue
- metrizamide
- mibefradil
- mifepristone
- milnacipran
- mirtazapine
- mitotane
- modafinil
- molindone
- morphine
- morphine liposomal
N
O
- olanzapine
- oliceridine
- olutasidenib
- ondansetron
- orphenadrine
- oxazepam
- oxcarbazepine
- oxycodone
- oxymorphone
P
- paliperidone
- palonosetron
- paraldehyde
- paroxetine
- pentazocine
- pentobarbital
- perphenazine
- pexidartinib
- phenelzine
- phenobarbital
- phenytoin
- pimavanserin
- pimozide
- posaconazole
- pregabalin
- primidone
- procarbazine
- promazine
- propiomazine
- propoxyphene
- protriptyline
Q
R
- ramelteon
- rasagiline
- remimazolam
- repotrectinib
- ribociclib
- rifabutin
- rifampin
- rifapentine
- risperidone
- ritonavir
- rizatriptan
S
- safinamide
- saquinavir
- secobarbital
- selegiline
- sertraline
- sibutramine
- sodium oxybate
- sotorasib
- st. john's wort
- stiripentol
- sumatriptan
- suvorexant
T
- tapentadol
- tasimelteon
- telaprevir
- telithromycin
- telotristat
- temazepam
- thioridazine
- thiothixene
- tizanidine
- tramadol
- tranylcypromine
- trazodone
- triazolam
- trifluoperazine
- triflupromazine
- trimipramine
- troleandomycin
- tryptophan
- tucatinib
V
Z
Subsys alcohol/food interactions
There is 1 alcohol/food interaction with Subsys (fentanyl).
Subsys disease interactions
There are 17 disease interactions with Subsys (fentanyl) which include:
- impaired GI motility
- infectious diarrhea
- prematurity
- acute alcohol intoxication
- drug dependence
- hypotension
- intracranial pressure
- respiratory depression
- gastrointestinal obstruction
- fever
- adrenal insufficiency
- liver disease
- renal dysfunction
- seizure disorders
- urinary retention
- arrhythmias
- biliary tract disease
More about Subsys (fentanyl)
- Subsys consumer information
- Check interactions
- Compare alternatives
- Reviews (12)
- Latest FDA alerts (14)
- Side effects
- Dosage information
- During pregnancy
- FDA approval history
- Drug class: Opioids (narcotic analgesics)
- Breastfeeding
- En español
Related treatment guides
Drug Interaction Classification
Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit. | |
Moderately clinically significant. Usually avoid combinations; use it only under special circumstances. | |
Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan. | |
No interaction information available. |
Further information
Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.