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Drug Interactions between ephedrine nasal and Mega-C-Acid Plus

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Minor

ascorbic acid ePHEDrine nasal

Applies to: Mega-C-Acid Plus (ascorbic acid) and ephedrine nasal

Acidic urine increases the elimination of ephedrine and pseudoephedrine and decreases the elimination half-life. The clinical significance is unknown. The therapeutic effects of these agents may be decreased.

References

  1. Brater DC, Kaojarern S, Benet LZ, et al. (1980) "Renal excretion of pseudoephedrine." Clin Pharmacol Ther, 28, p. 690-4
  2. Wilkinson GR, Beckett AH (1968) "Absorption metabolism and excretion of the ephedrines in man. I. The influence of urinary pH and urine volume output." J Pharmacol Exp Ther, 162, p. 139-47
  3. Kuntzman RG, Tsai I, Brand L, Mark LC (1971) "The influence of urinary pH on the plasma half-life of pseudoephedrine in man and dog and a sensitive assay for its determination in human plasma." Clin Pharmacol Ther, 12, p. 62-7

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Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.