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Drug Interactions between Demulen 1/35 and mitapivat

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

ethinyl estradiol mitapivat

Applies to: Demulen 1 / 35 (ethinyl estradiol / ethynodiol) and mitapivat

Mitapivat may reduce the effects of ethinyl estradiol in some women. If you are using ethinyl estradiol for birth control, you may be at increased risk for pregnancy or breakthrough bleeding. Talk to your doctor or pharmacist to determine if you should use an alternative or additional form of birth control during or after treatment with mitapivat. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Moderate

ethynodiol mitapivat

Applies to: Demulen 1 / 35 (ethinyl estradiol / ethynodiol) and mitapivat

Mitapivat may reduce the effects of ethynodiol in some women. If you are using ethynodiol for birth control, you may be at increased risk for pregnancy or breakthrough bleeding. Talk to your doctor or pharmacist to determine if you should use an alternative or additional form of birth control during or after treatment with mitapivat. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Drug and food interactions

Major

mitapivat food

Applies to: mitapivat

Grapefruit juice can increase the blood levels of mitapivat. This may increase side effects such as joint pain, increased uric acid blood levels, back pain, and in men, decreased reproductive hormones. You should avoid consuming grapefruit and grapefruit juice during treatment with mitapivat. However, if you have been regularly consuming grapefruit or grapefruit juice with the medication, then it is advisable for you to talk with your doctor before changing the amounts of these products in your diet, as this may alter the effects of your medication. Talk to your doctor if you have any questions or concerns. It is important to tell your doctor about all other medications you use, including vitamins and herbs. Do not stop using any medications without first talking to your doctor.

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Minor

ethinyl estradiol food

Applies to: Demulen 1 / 35 (ethinyl estradiol / ethynodiol)

Information for this minor interaction is available on the professional version.

Minor

ethinyl estradiol food

Applies to: Demulen 1 / 35 (ethinyl estradiol / ethynodiol)

Information for this minor interaction is available on the professional version.

Minor

ethynodiol food

Applies to: Demulen 1 / 35 (ethinyl estradiol / ethynodiol)

Information for this minor interaction is available on the professional version.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.