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Drug Interactions between coagulation factor x and Eliquis

This report displays the potential drug interactions for the following 2 drugs:

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Interactions between your drugs

Moderate

apixaban coagulation factor X

Applies to: Eliquis (apixaban) and coagulation factor x

GENERALLY AVOID: Based on their mechanisms of action, the pharmacologic activity of coagulation factor X is likely to be counteracted by direct and indirect factor Xa inhibitors. In vivo, factor X is converted from its inactive form to the active form, factor Xa, by the cleavage of a 52-residue peptide from the heavy chain.

MANAGEMENT: Concomitant use of coagulation factor X with direct and indirect factor Xa inhibitors should be avoided.

References

  1. (2022) "Product Information. Coagadex (coagulation factor X)." Bio Products Laboratory

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Drug and food interactions

No alcohol/food interactions were found. However, this does not necessarily mean no interactions exist. Always consult your healthcare provider.

Therapeutic duplication warnings

No warnings were found for your selected drugs.

Therapeutic duplication warnings are only returned when drugs within the same group exceed the recommended therapeutic duplication maximum.


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Drug Interaction Classification

These classifications are only a guideline. The relevance of a particular drug interaction to a specific individual is difficult to determine. Always consult your healthcare provider before starting or stopping any medication.
Major Highly clinically significant. Avoid combinations; the risk of the interaction outweighs the benefit.
Moderate Moderately clinically significant. Usually avoid combinations; use it only under special circumstances.
Minor Minimally clinically significant. Minimize risk; assess risk and consider an alternative drug, take steps to circumvent the interaction risk and/or institute a monitoring plan.
Unknown No interaction information available.

Further information

Always consult your healthcare provider to ensure the information displayed on this page applies to your personal circumstances.